Study on Complications, EfficAcy and Costs of Large Polypectomy
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1,000
- 主要终点
- complications of large polypectomy
研究概览
简要总结
Colonoscopy has been shown to reduce the incidence and mortality of colorectal cancer, through the recognition and removal of pre-cancerous lesions, which in most cases evolve with a sequence that goes through formation of high-grade dysplasia (HGD).
The probability of HGD increases with the increase of the lesion of the polyp itself. Lesions> 2 cm are present in 1% of colonoscopy screening. The resection of these lesions presents a greater technical difficulty and consequently a decrease in the efficiency. The rate of incomplete resection reported in the literature reaches 10% while that of recurrence / residual adenoma 16.4 / 31.7%.
The aim of the study SCALP is to evaluate the incidence of complications, efficacy and cost of endoscopic resection of colic lesions> 2cm in a setting of clinical practice in an unselected population
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult patients undergoing large endoscopic polypectomy
排除标准
- •pregnancy
- •incapacity to give informed consent
结局指标
主要结局
complications of large polypectomy
时间窗: 15 days
incidence of polypectomy-related adverse events
次要结局
- costs of large polypectomy(15 days)
- efficacy of large polypectomy(6 months)
研究者
Arnaldo Amato
MD
Valduce Hospital