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临床试验/CTRI/2020/08/027128
CTRI/2020/08/027128尚未招募1 期

Comparative evaluation of Triphala,Camellia (Green tea) and Chlorhexidine mouthwashes on gingivitis - A Randomized controled clinical trail

M Rajya lakshmi1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2020年8月17日最近更新:

试验速览

阶段
1 期
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
Plaque Index

研究概览

简要总结

Dental plaque is associated with the most prevalent oral diseases like dental caries and periodontal diseases. The removal of plaque is a determining component in the prevention of these diseases. The use of mechanical agents is a simple and cost effective method that has been demonstrated to be effective in control of gingivitis. Most of the individuals do not practice an acceptable standard of mechanical plaque removal due lack of dexterity in performing oral hygiene methods.Green tea, Camellia Sinensis from the family of Thea Cease is mostly cultivated in coasts of Caspian sea in North of Iran. Its remedial effects are associated with the polyphenol contents comprising catechin, epicatechin, gallocatechin, epigallocatechin, epicatechin gallate, and epigallocatechin gallate. Green tea consumption was found to lower the incidence of cardiovascular disease, diabetes, and obesity. Green tea is made solely with the leaves of C. sinensis that have undergone minimal oxidation during processing and hence it has more antioxidant and antibacterial properties. Studies have shown that green tea polyphenols inhibit the growth of oral and periodontopathic bacteria thereby preventing dental caries, halitosis, gingivitis, and periodontitis.

The beneficial effects of the natural products along with the lowerprevalence of side effects could enhance patient compliance and long-termusage. The purpose of the study is to evaluate the efficacy of the green tea intreatment of gingivitis

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 40.00 Year(s)(—)
性别
All

入选标准

  • Patients with minimum of 20 teeth.
  • Patients who have not taken periodontal treatment in past 6months.

排除标准

  • Pregnancy and lactating women Patients on antibiotic therapy from past 1 month Smokers Patients allergic to chlorhexidine, aloevera, triphala.

结局指标

主要结局

Plaque Index

时间窗: baseline | 15th day | 30th day

Gingival Index

时间窗: baseline | 15th day | 30th day

Bleeding Index

时间窗: baseline | 15th day | 30th day

次要结局

  • ..(.)

研究者

发起方
M Rajya lakshmi
申办方类型
Other [self]

研究点 (1)

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