Effects of the combination of the non-denatured collagen type II (UC-II®) and the Russian current muscle reinforcement on the pain and function of patients with osteoarthritis of the knee: a randomized double-blind clinical trial

niversidade Luterana do Brasil0 个研究点开始时间: 2019年7月8日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•Men and women 40 to 75 years of age (this age group is justified because it covers the subjects with the stage of evolution of osteoarthritis of degree I to III); Unilateral and bilateral knee osteoarthritisfor more than three months with classification I to III in the radiological classification of Kelgren Lawrence confirmed by orthopedic doctor; Functional score of Lequesne higher than 4.5; Availability of dedication to treatment during the study period (six months); Patient agrees not to initiate any new physical or drug therapy for knee OA during the study period; Have signed the Term of Free and Informed Consent.

•Grade IV knee osteoarthritis in the Kellgren-Lawrence radiological classification confirmed by orthopedist; Non-ambulatory; History of inflammatory arthropathy, septic arthritis, rheumatoid arthritis, inflammatory joint disease, uric acid gout, joint fracture, fibromyalgia, collagen genetic disease; Neurological diseases leading to cognitive deficits; History of asthma or type I or II diabetes; Psychiatric disorders; Symptomatic heart disease; Patients with clinical manifestations that do not allow the accomplishment of exercises; Presence of a skin or other type of skin disease at the level of the thigh; Urinary incontinence; Pregnancy; Alcoholism; Cancer; Patients with previous history of joint infiltration of corticoid or viscossuplementation in the knee in the last three months; History of trauma or knee surgery in the last six months; Three consecutive absences not justified physical rehabilitation.

发起方

niversidade Luterana do Brasil