Evaluation of Hysteroscopic Findings With Histopathologic Report of Endometrium in Patients With Postmenopausal Bleeding
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 90
- 主要终点
- evaluate hysteroscopic findings in women with postmenopausal bleeding and correlate them with histopathological results of the endometrium
研究概览
简要总结
To evaluate hysteroscopic findings in women with postmenopausal bleeding and correlate them with histopathological results of the endometrium., Sohag University Hospital Obstetrics and Gynecology department
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 45 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Postmenopausal women presenting with uterine bleeding
- •Age ≥ 45 years
排除标准
- •Women on hormone replacement therapy
- •Bleeding due to vulvar, vaginal, cervical, or urethral causes
- •Patients on anticoagulant therapy
- •Patients unfit for hysteroscopy
- •Refusal to participate
结局指标
主要结局
evaluate hysteroscopic findings in women with postmenopausal bleeding and correlate them with histopathological results of the endometrium
时间窗: 2 weeks
All patients in this study will be subjected to the following (as detailed in the attached patient's data sheet). I. Clinical Assessment * Detailed history including: * Duration since menopause * Pattern and duration of bleeding * Obstetric and medical history * General abdominal and pelvic examination II. Transvaginal Ultrasound (TVS) * Measurement of endometrial thickness * Assessment of uterine and adnexal pathology III. Hysteroscopic Examination Hysteroscopy will be performed using a rigid hysteroscope to evaluate: * Endometrial appearance * Presence of polyps, hyperplasia, or malignancy Hysteroscopic findings will be classified as: * Normal (proliferative, secretory, atrophic) * Abnormal (polyp, hyperplasia, carcinoma, fibroid) (1,3) Criteria suggestive of: * Hyperplasia: irregular thickened endometrium, increased vascularity (1,3) * Carcinoma: irregular necrotic tissue, atypical vessels, friable surface (1,3) IV. Endometrial Sampling • Directed biopsy will be taken from s
次要结局
未报告次要终点
研究者
Mahmoud Sabry Mahmoud
Mahmoud Sabry Mahmoud Mohamed
Sohag University