Impact of Neuropsychological Disorders on Visual Exploration, Walking Initiation and Walking in Multiple Sclerosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 32
- 试验地点
- 3
- 主要终点
- Cadence of walking (in cycles.min-1)
研究概览
简要总结
The study involves MS patients with and without neuropsychological disorders.
The patient will benefit from:
- A routine neuropsychological assessment, including a cognitive and emotional assessment
- A clinical examination
- A three-dimensional analysis of movement
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Understanding and able to speak French
- •Carriers of MS with relapsing remitting form (RRMS-RR) with an EDSS <4
- •No significant motor, cerebellar or somesthesia disorders of the upper limbs or visual disturbances (side to a visual EDSS <2)
- •Absence of corticosteroid intake in the last four weeks
- •Benefiting from health insurance coverage
- •Not showing any flare-ups or worsening of the disease in the last 6 weeks
- •No botulinum toxin injection for more than 4 months
排除标准
- •People with previous neurological pathologies, head trauma with loss of consciousness, psychiatric pathologies, serious general ailments, perceptual or dysarthric disorders preventing verbal communication or reading,
- •Treatment with psychotropic drugs (except benzodiazepines and hypnotics).
- •Refusal to participate after clear and fair information about the study.
- •Adults under tutorship, curatorship or safeguard of justice
- •With orthopedic treatment influencing walking
- •Pregnant woman
研究组 & 干预措施
patients without neuropsychological disorders
干预措施: Three dimensional gait analysis with eyetracking (Other)
patients with neuropsychological disorders
干预措施: Three dimensional gait analysis with eyetracking (Other)
结局指标
主要结局
Cadence of walking (in cycles.min-1)
时间窗: 60 days
The kinematics of the initiation of walking and walking will be appreciated thanks to the variables calculated at the level of the joints of the lower limbs as well as the spatio-temporal parameters without and with management of obstacles (taking a step, balloon)
Range of motion in the lower limbs in degrees
时间窗: 60 days
The kinematics of the initiation of walking and walking will be appreciated thanks to the variables calculated at the level of the joints of the lower limbs as well as the spatio-temporal parameters without and with management of obstacles (taking a step, balloon)
Step length (in m)
时间窗: 60 days
The kinematics of the initiation of walking and walking will be appreciated thanks to the variables calculated at the level of the joints of the lower limbs as well as the spatio-temporal parameters without and with management of obstacles (taking a step, balloon)
Walking speed (in m.s-1)
时间窗: 60 days
The kinematics of the initiation of walking and walking will be appreciated thanks to the variables calculated at the level of the joints of the lower limbs as well as the spatio-temporal parameters without and with management of obstacles (taking a step, balloon)
次要结局
- Ocular fixation time (measured in ms)(60 days)
- Displacements (in mm) during walking(60 days)
- Muscle contractions determined by the electromyogram (EMG) (mV)(60 days)
- Acceleration (in mm.s-2) during walking(60 days)
- Joint angles(60 days)