Circulatory Levels of Irisin in Response to Acute Resistance Training
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 28
- 试验地点
- 2
- 主要终点
- Serum irisin levels
研究概览
简要总结
Study the circulatory levels of irisin in response to one session of high-intensity resistance training in a group of healthy subjects.
详细描述
Objective: The purpose of this study is to study the circulating levels of irisin in response to acute high-intensity resistance training in a group of healthy young adults.
Sample: The sample will be comprised of adult men and women unpaid volunteers between the ages of 18 and 30. We will recruit 44 participants.
Pre- screening assessments: Informed consent, PAR-Q, Medical History and Exercise History will be used to determine health status and prior exercise experience. Menstrual cycle log will be required for female participants.
Pre-Intervention assessments (baseline):
- Anthropometric measurements and Body Composition: Height, triceps, thigh and calf skinfolds, biceps, thigh, hip, waist, and calf circumferences will be measured. Dual-energy x-ray absorptiometry (DEXA) will be performed to obtain body composition.
- Blood-related variables. Baseline glucose, lactate and hematocrit will be obtained from all participants prior to intervention. Lactate and Hematocrit will be obtained pre-intervention and post-intervention, and within 1 min post workout.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Participants between 18 and 30 years old
- •Males and Females
排除标准
- •Participants with known health problems such as cardiovascular, pulmonary or metabolic disease will be excluded.
- •Pregnant females will be excluded from the study.
- •Any adults found taking medications that affect endocrine or cardiovascular function will also be excluded from the study.
- •Individuals found to be less than 110 pounds will also be excluded due to the collection of blood during this study.
- •Participants that exercise more than three times per week or strength train more than twice per week will be excluded.
- •Individuals that have poor venous access or have expressed a fear of needles or having blood taken will also be excluded.
- •Cigarette smoking (current or those who quit within the previous 6 months
- •Hypertension
- •Overweight and obese
- •Pre-diabetics
研究组 & 干预措施
Intervention
The acute intervention will consist of 1 session of training following the program:
Resistance Training Exercises. Each participant in the intervention group will perform resistance-training exercises in the form of a circuit. The circuit will consist of 10 repetitions per exercise of 7 exercises: leg press, bent-over row, bench press, squats, dumbbell jump squats with raises, dead-lifts and weighted abdominal crunches, with approximately 30 sec of rest in between each exercise (based on the estimated time needed to move from one position to the next). Initial intensity 6-7 of RPE and ending the set at 9-10. Each participant will move through the circuit 3 times, with 2 to 3 minutes of rest between each round.
干预措施: exercise training (Other)
Control
No intervention
结局指标
主要结局
Serum irisin levels
时间窗: 1 day
Changes in irisin levels baseline, 45 min (during the training session), and post-training session
次要结局
- Body composition assessment, as measured by DEXA and anthropometry(1 day)
- Diet assessment: 24 hour recall and Food Preference Questionnaire(1day)
- Blood Glucose levels(1 session (1 day))
- Physical Activity assessment, as measured by Accelerometry.(1 week)
- Lactate levels(1 day)
- Hematocrit concentration(1 day)
- Physical Fitness levels as measured by 1 RM (repetition maximum) and Cardio-respiratory maximal test(1day)