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临床试验/NCT06119932
NCT06119932尚未招募不适用

Evaluation of One Burr Hole Evacuation for Subdural Hematoma

Assiut University1 个研究点 分布在 1 个国家目标入组 35 人开始时间: 2023年11月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
35
试验地点
1
主要终点
ClinicalEvaluation of evacuation for subdural hematoma by one burrhole

研究概览

简要总结

To evaluate the outcome of one burrhole evacuation for subdural hematoma and it has the same result of traditional two burrhole

详细描述

  • Subdural hematoma (SDH): abnormal Collection of Liquefied blood degradation underneath the dura matter (1.2.3).
  • one of the most frequent types of intracranial haemorrhage, That is still associated with significant morbidity (1.4.5).
  • The SDH: is a common disease in elderly Patient, and Its Incidence is highest in persons older than 70 Years of age (1.5).
  • Types of Subdural hematoma(18.19)

1- Acute: present within 48-72 hours of injury. 2. Sub-acute: manifest itself between 3-20 day. 3- Chronic (CH): produce symptoms from 3 weeks to several months after injury Risk Factors: (7.8.9.10.11.12)

  1. Trauma; mostly minor Trauma, Approximately two thirds of The Patients have suffered one. Reports exist of chronic SDH due to birth trauma in neonates.

  2. Advanced age: The elderly are at risk due to:

  3. brain atrophy, whereby The bridging veins are stretched and become more fragile.

  4. Older People tend to fall more often and Suffer minor head trauma.

  5. With increase age, The incidence of blood Thinner administration raises leading to increased risk for haemorrhage

  6. Chronic alcoholism:

  7. Gender: men, from all age groups, suffer higher rates of chsDH than woman.

  8. CoagulaPathy: Therapeutic anticoagulation and antiplatelet therapy.

  9. Medical Conditions: sepsis, hepatic failure, hemophilia, DIC and renal dialysis.

  10. Intracranial hypotension: as after ventriculoperitoneal shunt. clinical presentation (1.13)

  • Symptoms of increase intra cranial pressure: Headache, Nausea, vomiting.
  • Focal neurological deficit - (weakness, aphasia).
  • Disturbed conscious level (DCL)
  • Seizures
  • Imaging investigation:

CT brain (14.15)

  • Management : (1.6.16.17)

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Patients with subdural hematoma either unilateral or bilateral
  • •fit for surgery
  • •Chronic SDH
  • •Subacute SDH
  • •Age: patients older than 18 years old
  • •SEX: Both sex

排除标准

  • •Patients unfit for surgery
  • •Acute SDH
  • •subdural hyroma
  • •subdural empyema
  • •patient treated conservatively

结局指标

主要结局

ClinicalEvaluation of evacuation for subdural hematoma by one burrhole

时间窗: 72 hours post operative

* glasgo coma scale, * neurological deficit, * clinical symptoms (seizures) .

次要结局

  • Radiological evaluation for outcome(72 hours post operative)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mohammed lotfi abdelkareem

Neurosurgical resident

Assiut University

研究点 (1)

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