Contribution to Disease Diagnosis and Prognosis Based on the Fusion of Expert Knowledge, Nuclear Medicine Imaging and Artificial Intelligence (AI) Tools
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1
- 试验地点
- 1
- 主要终点
- Development of an artificial intelligence diagnostic program
研究概览
简要总结
Artificial intelligence algorithms for parathyroid adenoma detection in parathyroid scans The aim of the study is to develop programs for the automatic subtraction of planar and tomographic parathyroid images and for the localization of parathyroid adenomas using artificial intelligence tools.
Inclusion criteria Patients having undergone a double isotope parathyroid diagnostic examination using the standard Besançon University Hospital protocol (double injection of 123I and 99mTc, pinhole image, low energy high resolution (LEHR) and (single-photon emission tomography / Computed tomography) SPECT/CT +/- (positron emission tomography (PET) Choline).
Secondary endpoints Concordance between diagnoses made by nuclear physicians using both methods (current method and new treatment method).
详细描述
State of the art :
Planar scintigraphy of the parathyroid glands offers good diagnostic performance. The introduction of SPECT coupled with CT ten years ago has improved anatomical location, facilitating surgery.
With dual-isotope scans, the physician has to subtract the images to highlight the parathyroid adenomas, and use the SPECT/CT slices to pinpoint the exact location of the adenomas.
Several software packages, supplied by nuclear medicine image processing software publishers, are available on the market, but they require numerous actions on the part of doctors, which reduce reproducibility and necessitate a learning curve for the physician.
Research Hypothesis :
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Men and women over 18 years of age who underwent dual-isotope parathyroid scintigraphy.
- •No refusal to use data for research purposes
- •Retrospective data (after 13/04/2022: Date of posting of patient information in the department) and prospective data
排除标准
- •Patient refusal to use data for research purposes
- •Patients who did not benefit from the standard acquisition protocol (123I injection followed by 99mTc 3 hours after LEHR, PINHOLE and SPECT/CT acquisitions)
结局指标
主要结局
Development of an artificial intelligence diagnostic program
时间窗: through study completion, an average of 4 years
Development of an artificial intelligence diagnostic program
次要结局
- Development of an automatic program for subtracting double-isotope parathyroid images.(through study completion, an average of 2 years)