JPRN-jRCTs031200290已完成1 期
Safety evaluation of intranasal insulin administration during cardiac surgery for preventing postoperative delirium and cognitive dysfunction
Kawakami Akiko0 个研究点目标入组 27 人开始时间: 2021年1月12日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 27
研究概览
简要总结
Intranasal insulin administration 160 unit and less did not cause hypoglycemia. We need further study regarding minor complications.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 ot applicable（—）
- 性别
- All
入选标准
- •1)Patients scheduled elective cardiac surgery or major vascular surgery with cardiopulmonary bypass
- •2)Patients who are 20 years old or older
- •3)Patients with 1.5 mg/dL or less preoperative creatinine
- •4)Patients who had not undergone nasal surgery
- •5)Patients with written consent
- •6)Patients who are able to communicate with Japanese
排除标准
- •1 Patients had 23 or less preoperative MMSE score
- •2 Patients with insulin allergy
- •3 Patients under mechanical ventilation
- •4 Patients with severe psychological disorder
- •5 Patients with severe liver dysfunction
- •6 Patients with severe infectious diseases
- •7)Patients with severe cerebral infarction
- •8)Patients with dyspituitarism or adrenal insufficiency
研究者
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