Association Between Autism and Iron Deficiency in Children Diagnosed Autism
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 主要终点
- Aggressive autism picture
研究概览
简要总结
Association between Autism and Iron Deficiency in Children Diagnosed Autism
详细描述
Autism is a behaviorally defined complex neurodevelopmental syndrome characterized by impairments in social communication, by the presence of restricted and repetitive behaviors, interests and activities, and by abnormalities in sensory reactivity.
Autism is a severe, life-long developmental disorder that compromises functioning across multiple domains including social behavior, language, sensory function, and ritualistic/repetitive behaviors and interests. While the etiology of autism is complex and not fully understood, strong evidence from twin and family studies suggests a large genetic contribution .
Autism is caused by a combination of genetic and environment factors. Risk factors include certain infections during pregnancy such as rubella as well as valproic acid, alcohol or cocaine use during pregnancy.
The number of children known to have autism has increased dramatically since the 1980's.The reviews of epidemiology in estimating the global prevalence is that one to two cases of autism exist per 2,000 people, and about six per 1,000 people have Autistic Spectrum Disorders (ASD) .
According to the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), a guide created by the American Psychiatric Association used to diagnose mental disorders, people with Autism have:
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 2 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All children with autism above 2 years to and do not take supplements of iron or vitamins.
排除标准
- •• children less than 2 years old.
- •Children with other chronic neurological disorders or physical illness than Autism.
- •children with infection or other inflammatory conditions were excluded from the study,
- •children who received iron supplements during the last 3 months and / or who were on any dietary restrictions and children who are inpatients in rehabilitation centers
结局指标
主要结局
Aggressive autism picture
时间窗: One year
Identify the relationship between ID/IDA which may increase the severity of autistic symptoms in children with ASD.
次要结局
未报告次要终点
研究者
Mohammed Ali Mohammed Mostafa
Assiut university
Assiut University