Risk of Bleeding and Anticoagulation in Atrial Fibrillation: What Predictive Criterion Used?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 120
- 试验地点
- 5
- 主要终点
- scale : HAS-Bled
研究概览
简要总结
Atrial fibrillation (AF) is a rhythmic cardiac activity disorder disturbing hemodynamic blood flow. It is a public health problem with 600,000 to 1 million people involved in France which 2/3 are aged over 75 years. a FA untreated exposes the patient to a significant risk of embolism responsible for a rate stroke (stroke) ischemic estimated at 85%. The anticoagulant standard treatment helps prevent the occurrence of this complication.
However, oral anticoagulation also exposes patients to an increased risk of bleeding. The bleeding risk can be assessed using scales: several being proposed (HEMORR2HAGES, HAS-BLED, ATRIA and scores Shireman and Charlson ...).
moreover, in geriatric hospital care, every patient has a "standardized geriatric assessment" to assess and quantify functional capacity, autonomy, cognitive abilities, nutritional status, psychological state and its environment social.
Thus, the objective of the investigators study was to determine the frequency of each item of each bleeding risk assessment score and geriatric assessment in patients 80 and older hospitalized geriatric ward in the department and with anticoagulant.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 80 Years 至 —(Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •hospitalisation in geriatric unit
- •Atrial fibrillation treated by anticoagulant treatment (AVK or oral anticoagulation)
- •signed inform consent
排除标准
- •estimated lifetime less than 6 months
- •under guardianship or curatorship
- •without support person
结局指标
主要结局
scale : HAS-Bled
时间窗: at baseline
arterial hypertension, renal function, liver function, cerebrovascular accident...
scale : shireman
时间窗: at baseline
gender, age, hemorrhage, diabetes, anemia...
scale charlson
时间窗: at baseline
age, cardiovascular disease, lung disease, neurological disease, endocrinal disease, nephrology, liver disease, gastroenterology, cancer
scale : HEMORR2HAGES
时间窗: at baseline
hepatics diseases, alcoholism, cancer, thrombocytopenia, anemia and antecedent...
scale : ATRIA
时间窗: at baseline
anemia, serious kidney diseases, hypertension, antecedent...
scale : standardised geriatric assessment
时间窗: at baseline
comorbidities, cognition, mobility, pain, nutrition, living environment...
次要结局
- genotyping(at baseline)
- Occurrence of major bleeding event or not major(at baseline and 6 months)
