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临床试验/NCT02858518
NCT02858518已完成不适用

Risk of Bleeding and Anticoagulation in Atrial Fibrillation: What Predictive Criterion Used?

Centre Hospitalier Universitaire de Saint Etienne5 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2015年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
120
试验地点
5
主要终点
scale : HAS-Bled

研究概览

简要总结

Atrial fibrillation (AF) is a rhythmic cardiac activity disorder disturbing hemodynamic blood flow. It is a public health problem with 600,000 to 1 million people involved in France which 2/3 are aged over 75 years. a FA untreated exposes the patient to a significant risk of embolism responsible for a rate stroke (stroke) ischemic estimated at 85%. The anticoagulant standard treatment helps prevent the occurrence of this complication.

However, oral anticoagulation also exposes patients to an increased risk of bleeding. The bleeding risk can be assessed using scales: several being proposed (HEMORR2HAGES, HAS-BLED, ATRIA and scores Shireman and Charlson ...).

moreover, in geriatric hospital care, every patient has a "standardized geriatric assessment" to assess and quantify functional capacity, autonomy, cognitive abilities, nutritional status, psychological state and its environment social.

Thus, the objective of the investigators study was to determine the frequency of each item of each bleeding risk assessment score and geriatric assessment in patients 80 and older hospitalized geriatric ward in the department and with anticoagulant.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
80 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • hospitalisation in geriatric unit
  • Atrial fibrillation treated by anticoagulant treatment (AVK or oral anticoagulation)
  • signed inform consent

排除标准

  • estimated lifetime less than 6 months
  • under guardianship or curatorship
  • without support person

结局指标

主要结局

scale : HAS-Bled

时间窗: at baseline

arterial hypertension, renal function, liver function, cerebrovascular accident...

scale : shireman

时间窗: at baseline

gender, age, hemorrhage, diabetes, anemia...

scale charlson

时间窗: at baseline

age, cardiovascular disease, lung disease, neurological disease, endocrinal disease, nephrology, liver disease, gastroenterology, cancer

scale : HEMORR2HAGES

时间窗: at baseline

hepatics diseases, alcoholism, cancer, thrombocytopenia, anemia and antecedent...

scale : ATRIA

时间窗: at baseline

anemia, serious kidney diseases, hypertension, antecedent...

scale : standardised geriatric assessment

时间窗: at baseline

comorbidities, cognition, mobility, pain, nutrition, living environment...

次要结局

  • genotyping(at baseline)
  • Occurrence of major bleeding event or not major(at baseline and 6 months)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (5)

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