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临床试验/NCT05225493
NCT05225493Unknown不适用

Supporting Health Care Professionals in Hospital and Primary Care to Promote Adequate HIV Risk and Indicator Condition Driven Testing in Routine Care.

Erasmus Medical Center1 个研究点 分布在 1 个国家目标入组 1,500 人开始时间: 2020年1月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
1,500
试验地点
1
主要终点
The number of adequately performed HIV tests of identified HIV indicator conditions in relation to the total number of identified HIV indicator conditions by physicians in hospital settings during the project.

研究概览

简要总结

Patients are frequently evaluated by physicians for medical work-up of HIV indicator conditions in hospital and in primary care at the general practitioner. Testing for HIV is indicated with HIV indicator disorder but often omitted in clinical work-up. Besides the fact that HIV testing is forgotten, there are other reasons such as an underestimation of the risk of HIV in the event of indicator disorders, stigma and difficulties in discussing the test with a patient. Also and more relevant for primary care than for the hospital, practical challenges can exist for a patient to go to a laboratory, or costs are a hurdle.

This project focuses on improving HIV indicator condition driven testing in different settings of the HIV epidemic, initially in the Netherlands as low HIV prevalence setting followed by an assessment of its benefit in different international settings. A specific focus will also be on the Rotterdam area in the Netherlands which has a high prevalence of undiagnosed HIV in the Netherlands. The ultimate aim is to decrease the number of undiagnosed HIV in populations, improve the 90-90-90 HIV cascade of care goals particularly its first pillar, and to help supporting the UNAIDS goal to end HIV/AIDS

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Diagnosis of an HIV indicator conditions.

排除标准

  • Below 18 years of age
  • Recent HIV test (< 12 months, except for mononucleosis-like disease and STDs)

结局指标

主要结局

The number of adequately performed HIV tests of identified HIV indicator conditions in relation to the total number of identified HIV indicator conditions by physicians in hospital settings during the project.

时间窗: 3 year

The number of adequately performed HIV tests of identified HIV indicator conditions in relation to the total number of identified HIV indicator conditions by general practitioners in primary care during the project.

时间窗: 3 year

次要结局

  • The number of positive HIV tests in relation to the total number of HIV tests for identified HIV indicator conditions.(3 year)
  • The prevalence of HIV indicator conditions in primary care and hospitals.(3 year)
  • The incidence of HIV indicator conditions in primary care and hospitals.(3 year)
  • Acceptance of HIV testing in by patients, medical specialist and in primary care.(3 year)
  • The percentage of adequately HIV tested patients per HIV indicator condition and per medical specialism.(31 year)
  • A sensitive and specific supervised artificial Intelligence tool that recognizes risk factors for HIV and HIV indicator conditions through natural language processing (NLP) and supports the hospital and primary care in proactive HIV testing policies.(3 year)
  • The costs of pro-active HIV indicator case finding and relation to the savings and QALY's gained(3 year)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Casper Rokx

MD PhD

Erasmus Medical Center

研究点 (1)

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