A COMPARATIVE CLINICAL STUDY OF JATYAADI TAIL UTTARA BASTI AND URETHRAL DILATATION IN MOOTROTSANG (STRICTURE URETHRA)
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Cured : More than 75% relief in the complaints of patient.
研究概览
简要总结
Urethral stricture is a disease of Mootravaha Srotas in which there is narrowing of lumen of urethra causing obstructing symptoms. The stricture can develop anywhere along the length of male urethra and can be due to many etiologies. It is directly associated with quality of life of patients. As per Ayurvedic anatomy, disease related to genitourinary system falls under Mootravaha Srotas vyadhi. Acharya Sushruta has classified Mootraghata into 12 types.[i] Mootramarga Samkocha is not explained with separate title but the symptoms are similar to Mootrotsanga. Acharya Sushruta has explained Uttarbasti as treatment procedure of Mootrotsanga which is one of the types of Mootraghaat.[ii] Acharya Charaka has classified urinary disease like Mootra krichhra into 8 types.
Total 60 patients of Mootrotsang w.s.r. stricture of urethra will be selected from the O.P.D./ I.P.D. of the attached Hospitals of Uttarakhand Ayurved University. The study will be conducted on randomly divided 2 groups that means 30 patients in each group on the basis of criteria of inclusion and exclusion with detailed clinical history and physical examination and other necessary investigations. It will be a clinical study with pre-test and post-test design wherein a minimum of 60 patients suffering from Mootrotsang will be selected according to the inclusion criteria irrespective of their occupation, caste or creed. The parameters of sign and symptoms will be analyzed statistically. Subjects will be administered with Jatyaadi tail Uttara Basti and Urethral dilatation
Group A- 30 Patients will be given Jatyaadi tail Uttara Basti.
Group B- 30 Patients will be given urethral dilatation.
1. [i] Sushruta, Sushruta Samhita, Ayurved Tatvasandipika Hindi Commentary, Uttar Tantra, Varanasi: Chaukhamba Sanskrita Santhan; 2002.Adhyaaya, 58, verse 3-4:p. 539
2. [ii] Sushruta, Sushruta Samhita, Ayurved Tatvasandipika Hindi Commentary, Uttar Tantra, Varanasi: Chaukhamba Sanskrita Santhan; 2002.Adhyaaya, 58, verse 27-28:p. 544As per Ayurvedic anatomy, disease related to genitourinary system falls under Mootravaha Srotas vyadhi. Acharya Sushruta has classified Mootraghata into 12 types.[i] Mootramarga Samkocha is not explained with separate title but the symptoms are similar to Mootrotsanga. Acharya Sushruta has explained Uttarbasti as treatment procedure of Mootrotsanga which is one of the types of Mootraghaat.[ii] Acharya Charaka has classified urinary disease like Mootra krichhra into 8 types.
1. [i] Sushruta, Sushruta Samhita, Ayurved Tatvasandipika Hindi Commentary, Uttar Tantra, Varanasi: Chaukhamba Sanskrita Santhan; 2002.Adhyaaya, 58, verse 3-4:p. 539
2. [ii] Sushruta, Sushruta Samhita, Ayurved Tatvasandipika Hindi Commentary, Uttar Tantra, Varanasi: Chaukhamba Sanskrita Santhan; 2002.Adhyaaya, 58, verse 27-28:p. 544
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 25.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •Mild to moderate symptoms of urethral stricture.
- •Length of urethral stricture < 2cm.
- •Single urethral stricture.
- •Stage A (As per Devine Classification of stricture urethra on the basis of depth of the urethral stricture).
排除标准
- •Impacted calculus in the urethra and bladder neck.
- •BPH, Nephrotic syndrome, ARF, CRF, Neoplasm of lower urinary tract, Ca Bladder.
- •HIV Reactive, HbsAg reactive.
- •Congenital and severely symptomatic stricture urethra.
- •Multiple strictures (> 1).
结局指标
主要结局
Cured : More than 75% relief in the complaints of patient.
时间窗: 1 month
Marked Improvement : 50.1 - 75% relief in the complaints of patient.
时间窗: 1 month
Improvement : 25.1-50% relief in the complaints of patient.
时间窗: 1 month
Unchanged : Up to 25% relief in the complaints of the patients.
时间窗: 1 month
次要结局
- exacerbation in signs and symptoms(exacerbation in signs and symptoms)