CTRI/2020/04/024567招募中不适用
Assessment of optic nerve sheath diameter measured by bedside sonography as a predictor of raised intracranial pressure in adults.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- To study the correlation of optic nerve sheath diameter measured by bedside ultrasonography and the features of raised intracranial pressure on neuroimaging.
研究概览
简要总结
- Various studies have investigated Optic nerve sheath diameter (ONSD) as a marker for elevated intracranial pressure (ICP) and have found good correlation between the two. Further, ONSD diameter as measured by bedside ultrasonography, has been found to be well correlated with that measured with the help of MRI images.
- To the best of our knowledge, there is paucity of Indian studies which show correlation between the ONSD values as measured by ultrasonography and the signs of raised ICP on neuroimaging modalities (CT/MRI scans).
AIMS & OBJECTIVES
- To determine the normal optic nerve sheath diameter measured by bedside ultrasonography in the Indian population
- To study the correlation of optic nerve sheath diameter measured by bedside ultrasonography and the features of raised intracranial pressure on neuroimaging.
- To determine optimal cut off point of optic nerve sheath diameter to detect raised intracranial pressure
METHODOLOGY
Linear ultrasound probe will be used to measure the ONSD as the outer limits of the 2 hyperechoic lines, using electronic callipers, 3mm behind the papilla.
ONSD cut-off of 5mm will be used to define the presence of intracranial hypertension.
Patients with any one of the following findings on neuroimaging will be considered to have raised intracranial pressure-
- Midline shift > 3mm
- Sulcal effacement with significant oedema
- Compression of third ventricle
- Hydrocephalus
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)(—)
- 性别
- All
入选标准
- •1.Age > 18 years 2.Patient with clinical features of raised ICP such as headache, vomiting, blurring of vision, altered sensorium, GCS<
- •3.Moderate to severe traumatic brain injury (Glasgow coma scale <13) 4.Progressive neurological deterioration since admission 5.History of active malignancy with new onset confusion.
排除标准
- •1.Age <18 years 2.Orbital trauma 3.Orbital mass.
结局指标
主要结局
To study the correlation of optic nerve sheath diameter measured by bedside ultrasonography and the features of raised intracranial pressure on neuroimaging.
时间窗: Baseline
次要结局
- To determine the normal optic nerve sheath diameter by bedside ultrasonography in the Indian population.(2 years)
- To determine optimal cut off point of optic nerve sheath diameter to detect raised intracranial pressure(2 years)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
ONSD and Neurotoxicity in Liver TransplantLiver Transplant ComplicationsNCT03799770Mansoura University100
撤回
不适用
Optic Nerve Sheath Diameter and Intracranial Pressure (ICP) in ChildrenIntracranial HypertensionNCT02507063Anna Rominger
已完成
不适用
Correlation Between Optic Nerve Sheath Diameter and Neurological Deficit in Adult Patients With Suspected Ischemic StrokeIschemic StrokeNCT06492681Clinica Mexico19
招募中
不适用
trasound of the eye to detect raised intracranial pressureCTRI/2020/04/024567Fortis Memorial Research institute
已完成
不适用
Analysis of Change of Optic Nerve Sheath Diameter in in Patients Operated for Urological ReasonsCentral Nervous System DepressionAnaesthetic Complication NeurologicalNCT03485612Jagiellonian University69
