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临床试验/NCT07387887
NCT07387887尚未招募不适用

A Vision-Based Characterization of Human Movement Scaling in Large-Amplitude Tasks

Biruni University0 个研究点目标入组 26 人开始时间: 2026年1月30日最近更新:
干预措施

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
26
主要终点
Change in Movement Amplitude Across Repetitions

研究概览

简要总结

This pilot study investigates the feasibility of objectively quantifying movement amplitude and amplitude decay during large-amplitude exercises using RGB camera-based video analysis in healthy volunteers. Six large-amplitude exercises are recorded across repeated trials, with the first repetition clinically confirmed as the individual's maximum reference. Movement amplitude is quantified using pose-based kinematic measures and complemented by an exploratory self-supervised visual transformer approach to characterize repetition-wise changes relative to the reference execution. The study aims to determine whether camera-based methods can detect amplitude decay patterns and identify moments requiring clinical verbal cues, thereby supporting future objective monitoring and feedback in large-amplitude exercise training.

详细描述

Parkinson's disease is characterized by bradykinesia and impaired motor scaling, leading to reduced movement amplitude and diminished functional performance. Large-amplitude exercise approaches are widely used to counteract these deficits by promoting exaggerated movement execution and recalibration of internal movement perception. However, during repetitive exercise sets, individuals often demonstrate a gradual reduction in movement amplitude, a phenomenon known as amplitude decay, which typically requires verbal correction by a clinician.

Despite its clinical relevance, amplitude decay has not been objectively quantified, and movement quality is commonly assessed through visual observation alone. Marker-based motion capture systems, while accurate, are impractical for routine or remote use. RGB camera-based markerless analysis offers a low-cost and accessible alternative for objective movement assessment, particularly in telerehabilitation contexts where direct visual supervision is limited.

Participants and Study Design

A total of 22-26 healthy volunteers aged 18-45 years will be recruited. All participants will be capable of independent functional movement and will provide written informed consent prior to participation. The study follows a single-session, observational design.

Exercise Protocol

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Screening
盲法
None

盲法说明

This study employs single-level masking at the participant level. Participants are blinded to the specific analytical objectives and outcome measures of the study. While participants are informed that their movements are being video recorded during large-amplitude exercises, they are not informed about the criteria used to evaluate movement amplitude, repetition-wise changes, or the reference-based analysis approach.

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Ability to stand, walk, reach, step, and perform sit-to-stand movements independently without assistance.
  • No self-reported or clinically diagnosed neurological, musculoskeletal, or vestibular disorders.
  • Normal or corrected-to-normal vision sufficient to follow visual instructions.

排除标准

  • History of neurological disorders (e.g., Parkinson's disease, stroke, multiple sclerosis, traumatic brain injury).
  • History of major musculoskeletal injury or surgery affecting upper or lower extremities that limits movement.
  • Presence of balance disorders or vestibular dysfunction.
  • Cardiovascular, respiratory, or metabolic conditions that may limit safe participation in physical exercise.
  • Current pain, dizziness, or excessive fatigue during movement or exercise.
  • Pregnancy or any condition for which moderate-intensity physical activity is contraindicated.
  • Use of assistive devices for walking or balance.
  • Refusal or inability to provide consent for RGB video recording.

研究组 & 干预措施

Healthy Volunteers - Observational Arm

Experimental

No Intervention / Observational: All participants are healthy adult volunteers who perform standardized large-amplitude exercises while being video recorded. No therapeutic intervention, randomization, or group allocation is applied. All participants undergo the same exercise protocol and data collection procedures.

干预措施: Large-Amplitude Exercise Observation and Video Recording (Other)

结局指标

主要结局

Change in Movement Amplitude Across Repetitions

时间窗: Baseline

Movement amplitude will be quantified for each repetition of six large-amplitude exercises using normalized, RGB camera-based pose estimation. Amplitude decay will be defined as the change in movement amplitude across repeated executions within each exercise, reflecting repetition-related reduction in movement scali

次要结局

  • Reference-Based Visual Similarity Score(Baseline)
  • Repetition-Wise Amplitude Decay Trend(Baseline)
  • Association Between Kinematic Amplitude and Visual Representation Measures(Baseline)

研究者

发起方
Biruni University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Guzin Kaya Aytutuldu

Assistant Professor

Biruni University

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