PACTR201805003381361已完成未知
Modifying Intestinal Integrity and MicroBiome in severe Malnutrition with LEgume-based feeds [MIMBLE Study]: A Pilot Study
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 90
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 6 Month(s) 至 5 Year(s)（—）
- 性别
- All
入选标准
- •Anthropometric features of severe acute malnutrition as per WHO Child Growth Standards (2006):
- •1.Marasmus: Mid-upper arm circumference (MUAC) <11.5cm or Weight-for-height Z-score (WHZ) < -3
- •2.Kwashiorkor: Symmetrical pitting oedema involving at least the feet irrespective of WHZ score or MUAC
- •3.Guardian or parent willing and able to provide consent
排除标准
- •Children with severe acute malnutrition with a very high risk of early death will be excluded:
- •¿Impaired consciousness: one of prostration (inability to sit unsupported or inability to breast feed if < 9months) or coma (inability to localise a painful stimulus) after correction of hypoglycaemia if present.
- •¿Shock: two or more of capillary refill time > 3s, lower limb temperature gradient or weak radial pulse volume.
- •¿Severe dehydration: Sunken eyes and reduced skin turgor in the presence of diarrhoea (3 or more episodes of profuse and watery stool)
- •¿Respiratory distress: increased work of breathing and hypoxia (oxygen saturation < 90% in air)
- •Additionally children who cannot complete accurate dietary recall will be excluded:
- •¿Exclusively breast-fed infants
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