Comparison of subarachnoid block characteristics using pre-mixing versus sequential injection of fentanyl and hyperbaric ropivacaine (0.75%)
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- To compare the total duration of sensory block in both the groups.
研究概览
简要总结
The present prospective study will be conducted in the department of anaesthesia and critical care, PGIMS Rohtak. Written informed consent will be taken from patients included . then assessment and comparison of subarachnoid block characteristics using pre-mixing versus sequential injection of fentanyl and hyperbaric ropivacaine 0.75%.Data will be compiled and analysed with appropriate statistical tests.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •The study will include 80 patients of either sex of age 18-65 years, belonging to American Society of Anesthesiologists (ASA) physical status of I-II scheduled for lower Limb surgery sub-arachnoid block.
排除标准
- •Patient refusal to participate Contraindication to spinal anaesthesia Known to allergy to local anaesthesia Pregnancy.
结局指标
主要结局
To compare the total duration of sensory block in both the groups.
时间窗: Sensory block will be assessed at 1 minute interval by using alcohol swab in the mid-clavicular line, bilaterally, till T10 level is achieved. Time will be noted and surgery will be started. However, sensory level will be checked every 1 minute thereafter, till the time the sensory level is noted to be the same for 2 consecutive intervals. This level will be taken as the maximum sensory level achieved and last but one reading, in minutes, will be taken as time to achieve the maximum level.
次要结局
- Onset, highest level attained, motor block, hemodynamics parameters.(Motor blockade will be assessed every 5 minutes and the maximum motor level achieved at 20 minutes from the intrathecal injections of drugs , as per modified bromage scale.)
研究者
Dr Preeti Gehlaut
Pt B D Sharma PGIMS, Rohtak