Tolerance to Light for Patients Suffering From Keratitis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Light intensity
研究概览
简要总结
In order to develop an innovative device to study infectious keratitis, we need to illuminate the cornea of patients suffering from an infectious keratitis with red or near-infrared light. Because of technical reasons the shortest possible wavelength (red) presents advantages.
详细描述
The aim of this preliminary study is to measure the maximal intensity tolerated during illumination with 6 wavelength corresponding : 2 red, 2 far red and 1 near infrared lights in order to determine the shortest wavelength well tolerated by patients, in comparison with the standard blue light illumination.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Social security insurance
- •Suspected infectious keratitis (clinically defined. No lab testing required)
- •Signed informed consent
排除标准
- •Major Blepharospasm
- •Aphakia (absence of lens)
- •Pregnant woman
- •Nursing mother
研究组 & 干预措施
Light exposure
The keratitis eye of the patient is exposed to 6 lights with increasing intensity according to a constant speed.
The patients switch off the light when the discomfort is too elevated
干预措施: Light exposure (Device)
结局指标
主要结局
Light intensity
时间窗: At the inclusion
For each wavelength, the highest light intensity tolerated by the patient is measured (mWatts/cm² )
次要结局
- Severity of the keratitis(At the inclusion)