Measured glomerular filtration rate using Diethylenetriaminepentaacetic acid (DTPA) renal scan versus estimated glomerular filtration rate using modified Schwartz formula in critically ill children: A prospective observational, analytical study.

The Director0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•All children aged (corrected age) 1 month to 12 years admitted in PICU, will be included in the study within 24 hours of admission to PICU with stable hemodynamic parameters (i.e Achieved immediate resuscitation goals (as directed by the treating physician) including fluid resuscitation AND/OR vasoactive therapy to achieve capillary refill of <=2 secs, >5th percentile mean arterial blood pressure (MABP) for age, sex and length/height, normal pulses volume with no differential between peripheral and central pulses and urine output more than 1ml/kg/hour for at least 6 hours. Central venous pressure >=8 cmH2O (if measured), central venous oxygen saturation >=70% (if measured) AND/OR cardiac index between 3.3 and 6.0 L/min/m2 (if measured) and remain stable for 6-hours.

•1. Patient with >= Stage 4 chronic kidney disease (defined by an estimated glomerular filtration rate <30 mL/min/ 1.73 m2), end-stage kidney disease on chronic dialysis, kidney transplantation or already received dialysis in PICU.
•2. Patient requiring renal replacement therapy (RRT) at admission/prior to enrollment.
•3. Patient with known or suspected obstructive etiology for AKI.
•4. Patients with severe acute malnutrion as per World Health Organization (WHO) classification (presence of bipedal edema of nutritional origin, weight-for-height or weight-for-length: Z-score <â??3, presence of visible severe wasting), a mid-upper-arm-circumference <11.5cm (in children > 6months <60 months).

发起方

The Director