NCT04283110Unknown不适用
Impact of Adding Midzolam to Bupavicaine 0.5% in Regional Spinal Anaesthesia on Maternal Middle Cerebral Artery Velocimetry in Parturients With Severer Preeclampsia
Minia University1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2019年1月12日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Measuring Pulsatality index and resistive index of maternal middle cerebral artery
研究概览
简要总结
Trial to use GABA mimetic action of midazolam to ameliorate the severe preeclampsia induced neuronal excitotoxicity using middle cerebral artery transcranial doppler resisitive vasculer indices to evaluate . Secondery goal is to study end organ injury
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •All parturients with severe preeclampsia for urgent C.S
排除标准
- •Ladies refusal to participate. Refusal to have spinal anesthsia
研究组 & 干预措施
Midazolam group
Active Comparator
Midazolam group will receive 1 mg intrathecal midazolam once during induction for anethesia
干预措施: intrthecl midazolam (Drug)
结局指标
主要结局
Measuring Pulsatality index and resistive index of maternal middle cerebral artery
时间窗: 2 months
Resistive vasculer indices outcome after intrthecal midazolam injection
次要结局
未报告次要终点
研究者
Mina Maher
dr
Minia University
研究点 (1)
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