2023-506062-31-01招募中4 期
Comparison of different doses of perineural dexmedetomidine as adjuvans to ropivacaine 0,67% for interscalene plexus block in association with 10 mg intravenous dexamethasone: a single center, double blinded, randomised controlled trial.
Algemeen ziekenhuis Rivierenland1 个研究点 分布在 1 个国家目标入组 260 人开始时间: 2023年11月9日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 发起方
- 入组人数
- 260
- 试验地点
- 1
- 主要终点
- Length of analgesia ( time untill intake of analgeticum )
研究概览
简要总结
To look at the efficacy of different doses of perineural dexmedetomidine to prolong the length of the analgetic block after a interscalene plexus block.
入排标准
- 年龄范围
- 18 years 至 65+ years（65+ Years, 18-64 Years）
- 接受健康志愿者
- 否
入选标准
- •Patients scheduled for elective shoulder surgery
排除标准
- •Chronic pain
- •Contra-indications for peripheral nerve block
- •Allergy for ropivacaine, dexmedetomidine or dexamethasone
- •> 80 years old
- •second degree AV block
- •Emergency operations
- •No informed consent
- •Medical history of cardial, renal or hepatic failure
- •Dehydratation
- •Neurologic deficits or neuropathia of the brachial plexus
结局指标
主要结局
Length of analgesia ( time untill intake of analgeticum )
Length of analgesia ( time untill intake of analgeticum )
次要结局
- Lenght of sensoric block
- Length of motoric block
- Percentage of postoperative nausea and vomiting first 48 hours
- Time to recovery after anesthesia
- Percentage of side effects during anesthesia ( hypotension, bradycardia )
- Numeric Rating Scale score for pain the first 48 hours
- Cumulative opioid consumption over 48 hours
研究者
herve vanden eede
Scientific
Algemeen ziekenhuis Rivierenland
研究点 (1)
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