A Randomized, Double Blind and Crossover Study Investigating the Effect of Whole Versus Processed Orange Consumption on Satiety in Healthy Volunteers
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Self reported hunger and fullness score by Visual Analogue Scale
研究概览
简要总结
This is a human dietary intervention study that is randomized and crossover in design with 4 treatment arms consisting of control, orange juice,whole orange, and processed whole orange to investigate the satiety effects of the treatments in healthy volunteers. Self reported hunger and fullness scores by Visual Analogue Scale (VAS) form were collected at different time points prior to and post consumption of each treatment.
详细描述
This is a human dietary intervention study that is randomized and crossover in design with 4 treatment arms consisting of control, orange juice,whole orange, and processed whole orange to investigate the satiety effects of the treatments in healthy volunteers. Self reported hunger and fullness scores by Visual Analogue Scale (VAS) form were collected at different time points prior to and post consumption of each treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 21 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Gender: male or female(postmenopausal women only)
- •Age at start of the study: males ≥ 21and ≤ 65 years and females ≥ 50 and ≤ 65 years
- •Body Mass Index (BMI) ≥ 18.5 and ≤ 27 kg/m2
- •Apparently healthy: measured by questionnaire, no reported current or previous metabolic diseases or chronic gastrointestinal disorders
- •Reported dietary habits: no medically prescribed diet, no slimming diet, used to eating 3 meals a day
- •Reported intense sporting activities ≤ 10h/w
- •Reported alcohol consumption ≤21 units/w
- •Informed consent signed
- •Recruitment form filled out
排除标准
- •Dislike, allergy or intolerance to test products
- •Possible eating disorder (measured by SCOFF questionnaire score >1)
- •Eating habits questionnaire score >14
- •Reported medical treatment that may affect eating habits/satiety
- •Pre menopausal women
研究组 & 干预措施
Control
Water control (240 ml)
干预措施: Processed orange juice (Dietary Supplement)
Orange Juice
Orange juice, 240 ml. Commercial orange juice
干预措施: Processed orange juice (Dietary Supplement)
Whole orange
Whole orange, 240 ml. Whole orange, blended to include all edible orange material.
干预措施: Processed orange juice (Dietary Supplement)
processed orange juice
Processed orange juice, 240 ml. Experimental orange juice processing
干预措施: Processed orange juice (Dietary Supplement)
结局指标
主要结局
Self reported hunger and fullness score by Visual Analogue Scale
时间窗: baseline to 2 hours
次要结局
- Overall liking by '9 point hedonic scale'(baseline to 2 hours)
研究者
Jeremy Paul Edward Spencer
Professor of nutritional medicine
University of Reading