PSG and Neuroendocrine Hormones in Subjective Cognitive Impaired Patients With Transformed Migraine
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 161
- 试验地点
- 1
- 主要终点
- Polysomnography
研究概览
简要总结
Transformed migraine is the most common and challenging subtype of chronic daily headache disorders35. Patients with transformed migraine often report an evolutionary process that occurs over months or years in which headaches increase in frequency, change characteristics and ultimately result in patterns of daily or near-daily headaches resembling a mixture of tension-type headache and migraine.
详细描述
The present study aimed to investigate the presence and frequency of cognitive affection in patients with transformed migraines, as well as to analyze the association of cognitive affection with clinical features and headache impact, anxiety, depression, and quality of sleep.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients included were adults with clinically confirmed of chronic migraine
排除标准
- •Primary headache disorder other than migraine
- •Secondary headache disorders other than medication-overuse headache or unclassified headache, or
- •Aged under 18 years or older than 65 years
结局指标
主要结局
Polysomnography
时间窗: 24-72 hours
PSG was carried out for 41 patients with subjective cognitive impairment and 41 age and sex-matched controls. PSG with standard EEG montage that includes bilateral EOG and four EEG leads were used. A single attended overnight PSG study was performed at the Clinical Neurophysiology Unit of Mansoura University Hospitals. Patients were studied in a quiet, darkened room with no medications were used to induce sleep. All participants underwent one night of laboratory-based PSG.
次要结局
未报告次要终点
研究者
Ahmed Esmael
Assistant Prof of Neurology
Mansoura University Hospital