Does Meal Timing Affect Energy Expenditure
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 11
- 试验地点
- 2
- 主要终点
- Energy expenditure (calories burned)
研究概览
简要总结
The purpose of this study is to find out if meal timing affects calories burned and blood sugar levels.
详细描述
10 overweight adult men and women will eat according to two different eating schedules: grazing and time-restricting feeding ("early eating"). While on each eating schedule, metabolism (calories burned) will be measured during a 24-hour stay in a respiratory chamber. Glucose levels-as well as key diurnal rhythms such in heart rate-will also be measured continuously. This study requires two 1-week periods of participation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Are 20-45 years of age
- •Have a weight between 150 and 220 lbs
- •Have a body mass index between 25 and 35 kg/m2 inclusive (a number calculated from your height and weight)
- •If you are a female, have a regular menstrual cycle that is between 25 and 35 days long
- •If you are female, had your period within the last 35 days
- •Regularly go to sleep between 9:30 pm and 12:00 am
- •Regularly eat dinner 9 or more hours after eating breakfast
- •Are willing to have about 2/3 cup of your blood stored for future research related to this study
排除标准
- •Have diabetes or are on anti-diabetes medication
- •Suffer from significant cardiovascular, renal (kidney), cardiac (heart), liver, lung or nervous system disease
- •Have stomach or intestinal problems
- •Regularly use medications such as steroids, beta blockers, adrenergic-stimulating agents, and laxatives
- •Take any medications or supplements known to affect sleep, circadian rhythms, or metabolism (with the exception that certain forms of birth control are allowed)
- •Have abnormal lab work that is clinically significant in the opinion of the study physician
- •Are pregnant or lactating
- •Take the Depo Provera shot, or use an Interuterine Device (IUD) or hormone patch for birth control
- •If you are on hormonal birth control, have been on a stable dose for less than 3 months
- •Have smoked or used nicotine/tobacco products within the last 3 months
- •Regularly do competitive sport training
- •Perform overnight shift work an average of one or more times per week
- •Have an irregular sleep schedule
- •Have an irregular eating schedule
- •Regularly drink 3 or more drinks of alcohol per day
- •Are not able or are unwilling to eat only the food and drink served to you by Pennington Biomedical, while in the study
- •Are not able or are unwilling to refrain from strenuous exercise while participating in the study
- •Are not able to spend 2 separate full days (for about 25 hours each) at Pennington Biomedical
- •Are not able to maintain a consistent sleep schedule while participating in the study
- •Are not able to maintain a consistent eating schedule while participating in the study
- •Are not able to stop drinking coffee and other caffeine-containing drinks on the day of and day prior to testing
研究组 & 干预措施
Grazing
Participants will eat meals spread over the course of the day ("grazing").
干预措施: Grazing (Behavioral)
Time-restricted feeding (early eating)
Participants will eat meals only in the early part of the day (early lunch and very early dinner).
干预措施: Time-restricted feeding (early eating) (Behavioral)
结局指标
主要结局
Energy expenditure (calories burned)
时间窗: 2 days
次要结局
- Blood sugar levels(2 days)
研究者
Courtney Peterson
Instructor
Pennington Biomedical Research Center