Does Irritable Bowel Syndrome Improved by Low FODMAP Diet ?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 112
- 试验地点
- 1
- 主要终点
- Fructose expiration rate (ppm)
研究概览
简要总结
The patients having a syndrome SII would be more intolerant in the fructose than the healthy subjects and would benefit from a fructose diet but also from the fructans which contain some fructose. The intolerance in the fructose is diagnosed thanks to a respiratory test after absorption of fructose. However, the eviction of the fructose is sometimes recommended to the patients without having realized beforehand the test of intolerance.
详细描述
The main objective is to evaluate the efficacy of the FODMAPS diet on IBS symptoms and to correlate the results with the respiratory test
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •older than 18, patients with IBS, patients with no organic disorders, patients informed and agreed to participate
排除标准
- •patients with sclerodermia, diabetes, obesity, anorexia, colo-rectal surgery, patients with small intestinal bacterial overgrowth, pregnancy
研究组 & 干预措施
Low FODMAPS diet and positive breath testing for fructose
Patients with breath testing positive have a low FODMAPS diet. The test will be considered as positive if we observe an increase of more than 20 ppm of H2 and/or CH4 on a sample with regard to the basal concentration
干预措施: Low FODMAPS diet (Other)
negative breath testing for fructose
patients with negative breath test have a low FODMAPS diet
干预措施: Low FODMAPS diet (Other)
结局指标
主要结局
Fructose expiration rate (ppm)
时间窗: Day 15
Estimate the value of the fructose test to predict the efficiency of a diet excluding the fructose and its by-products on the digestive symptoms of the patients having a Syndrome of the irritable bowel.
次要结局
未报告次要终点