A mechanistic, prospective, longitudinal, observational, biobank study of postoperative anaemia and inflammation in patients having cardiac surgery

Department of Critical Care, The University of Melbourne0 个研究点目标入组 60 人开始时间: 2023年10月4日最近更新: 2023年10月9日

适应症

试验速览

暂无简介。

•Undergoing cardiac surgery that is not CABG and/or cardiac valve procedures (i.e., ascending aorta or root replacement, solid organ transplantation, etc.)
•End-stage renal failure requiring dialysis
•Active solid organ malignancy
•Taking antibiotic therapy for active infection at time of operation
•Acquired/clonal haematological malignancies (including leukaemia, lymphoma, myeloma, myelodysplasia, or aplastic anaemia)
•Haemoglobinopathy (including a-globin and/or ß-globin gene mutations [thalassaemia] and sickle cell trait)
•Inherited red cell membrane disorders (including glucose-6-phosphate-dehydrogenase and pyruvate kinase deficiency)
•Active haemolytic processes (mechanical or autoimmune)
•Preoperative requirement for erythropoiesis stimulating agents
•Age < 18 years
•Pregnancy or breastfeeding
•Surgical plan requiring off-pump technique
•Preoperative Hb < 130 g/L if male and < 120 g/L if female
•Preoperative C-reactive protein (CRP) concentration > 5 mg/L
•Emergency surgery (i.e., following decision to operate, the patient proceeds to surgery before the next business day)
•Not willing to attend for blood tests following discharge.

发起方

Department of Critical Care, The University of Melbourne