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临床试验/CTRI/2017/02/007922
CTRI/2017/02/007922已完成2 期

Comparative Evaluation Of Anaesthetic Efficacy Of warm, Buffered And Conventional 2% Lignocaine For The Success Of Inferior Alveolar Nerve Block In Mandibular Primary Molars- A Randomized Clinical Controlled Trial.

Reenu Sarah Kurien1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2015年11月30日最近更新:

试验速览

阶段
2 期
状态
已完成
发起方
入组人数
50
试验地点
1
主要终点
1.Anaesthetic efficacy

研究概览

简要总结

This study is a randomized, double blinded, split mouth clinical trial, comparing the anaesthetic efficacy and patient’s pain reaction to warm lignocaine, buffered lignocaine and conventional 2% lignocaine during pulp therapy in primary mandibular molars. 50 patients were randomly divided into 2 groups and were given conventional lignocaine on one visit on one side and either buffered or warmed lignocaine on the other side during the next visit. The results showed that the pain on administration, mean onset of anaesthesia, pain during pulp therapy, the parameters of the SEM score and the duration of anaesthesia were all significantly lower for the buffered and warmed solutions compared to the conventional solution. However there was no significant difference on comparing the warmed and buffered groups with each other. Thus it can be concluded that modifying local anaesthesia by either buffering it or warming it can be beneficial in reducing the pain on injection and during pulp therapy, especially in children.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
6.00 Year(s) 至 12.00 Year(s)(—)
性别
All

入选标准

  • 1.patients having deep dentinal caries extending through half the dentinal depth wrt 74, 75, 84, 85
  • patients complaining of mild to moderate pain.
  • 3.teeth with vital pulp 4.children with frankl behaviour rating of 3 or 4 5.patients whose parents/guardians give consent 6.subjects should be free of systemic disease 7.the agreement to comply with study visits and procedures.

排除标准

  • 1.patients who are physically or medically compromised/ systemic disease 2.patients with allergies to local anaesthetics, sulphites or sodium bicarbonate 3.patients on any medication 4.presence of abscess or sinus openings at the site of injection or at the tooth involved.
  • 5.children with frankl behaviour rating of 1 or 2.

结局指标

主要结局

1.Anaesthetic efficacy

时间窗: 3-5 hours

2.The patient’s pain reaction

时间窗: 3-5 hours

次要结局

  • 1.Pain during administration of anaesthesia(2.Onset of anaesthesia)

研究者

发起方
Reenu Sarah Kurien
申办方类型
Other [self]

研究点 (1)

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