NCT02917486已完成不适用
EC-MOTION : ExtraCorporeal Membrane Oxygenation and Therapeutic Drug Monitoring of Drugs of infectION
Rennes University Hospital2 个研究点 分布在 1 个国家目标入组 44 人开始时间: 2016年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 44
- 试验地点
- 2
- 主要终点
- Measure exposure to piperacillin
研究概览
简要总结
The objective of the study is to investigate the exposure difference between antibiotic studied patients in intensive care with Extracorporeal Membrane Oxygenation and patients without Extracorporeal Membrane Oxygenation.
The exhibition is evaluated by population pharmacokinetic modeling.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age over 18 years
- •Hospitalisation in intensive care
- •Treatment with ECMO or without ECMO
- •Introducing sepsis treated with an anti-infective molecule studied (piperacillin) for less than 48 hours
- •With an arterial catheter
- •Patient Information or their next of kin according to the patients status.
排除标准
- •Pregnancy
- •Major person under legal protection (backup justice, trusteeship, quardianship), person deprived of liberty
结局指标
主要结局
Measure exposure to piperacillin
时间窗: Day 1
evaluated by population pharmacokinetic modeling and is defined by the time during which the antibiotic concentration is greater than 4 times the critical concentration of the germ to treat
次要结局
未报告次要终点
研究者
研究点 (2)
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