ISRCTN17616323已完成不适用
Oral vitamin B12 supplementation and cognitive performance in elderly people
The Netherlands Organisation for Health Research and Development (ZonMw) (Netherlands)0 个研究点目标入组 195 人开始时间: 2005年12月20日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 195
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Men and women aged 70 years or older
- •2. Mild vitamin B12 deficiency defined as vitamin B12 concentration between 100 and 300 picomol/L and MMA concentration greater than 0.32 micromol/L and creatinine concentration less than 120 micromol/
排除标准
- •1. Severe cognitive impairment
- •3. Gastrointestinal surgery
- •4. Use of vitamin B12 injections or supplements containing > 50 micrograms vitamin B12 and/or 25 micrograms folic acid
- •5. Less than 90% compliance during a 2 week placebo run in period
- •6. No written informed consent
- •7. Participation in other studies
研究者
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