跳至主要内容
临床试验/NCT07141849
NCT07141849招募中不适用

Comparison of Changes in Neuromuscular and Functional Performance Due to Block Periodization or Traditional Power Training in Persons With Parkinson's Disease.

University of Miami1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年8月29日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
60
试验地点
1
主要终点
Change in neuromuscular performance as measured by Watts

研究概览

简要总结

This study will compare the effects of high-speed power resistance training to periodized training, which includes cycle of hypertrophy, strength and power, on measures of muscle strength and power and tests of daily performance in older adults with Parkinson's disease.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
50 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Parkinson's Disease Hoehn & Yahr Stages 1-3
  • •Able to walk 50m unassisted
  • •Able to understand and communicate in English

排除标准

  • •Uncontrolled cardiovascular or other neuromuscular disease that prevent participation in a training program
  • •Any systemic inflammatory or autoimmune conditions such as rheumatoid arthritis, or other serious concomitant medical illness
  • •Unresolved injury or surgery to the upper or lower limbs that prevents weight training.

研究组 & 干预措施

Power Resistance Training

Active Comparator

Participants will receive high-speed power resistance training, twice per week for at least 24 sessions for up to 12 weeks.

干预措施: Power Resistance Training (Behavioral)

Periodized Resistance Training

Experimental

Participants will receive periodized resistance training twice per week for at least 24 weeks.

干预措施: Periodized Resistance Training (Behavioral)

结局指标

主要结局

Change in neuromuscular performance as measured by Watts

时间窗: Baseline, 12 weeks

This test measures the power a person can produce at maximal speed using loads of 20%, 40%, 60%, 80%, and 90% of 1RM for the chest press and leg press. Power shows how fast a person can do work. Unit of measure is Watts.

Change in neuromuscular performance as measured by 1-repetition maximum (1RM)

时间窗: Baseline, 12 weeks

Maximal load that can be lifted in one repetition (1RM) will be assessed in both leg press and chest press exercises. The loads on the testing equipment will be increased across 5 to 7 testing repetitions. The persons 1RM will be the highest load the person can move through the range of motion of the exercise. There are no minimum or maximum scores for this test. The higher the 1RM the stronger the person is. The unit of measurement is kilograms.

次要结局

  • Change in Distance of the Seated Medicine Ball Throw.(Baseline, 12 weeks)
  • Change in the time required to complete the timed Up-and-Go Test.(Baseline, 12 weeks)
  • Change in the Speed of the Ten-Meter Walk Test.(Baseline, 12 weeks)
  • Change in Time for the Five Times Sit-to-Stand Test.(Baseline, 12 weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Joseph Signorile

Professor

University of Miami

研究点 (1)

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