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临床试验/NCT02471612
NCT02471612已完成不适用

Comparative Analysis of APACHE II and P-POSSUM Scoring Systems in Predicting Postoperative Mortality in Patients Undergoing Emergency Laparotomy

Tata Main Hospital1 个研究点 分布在 1 个国家目标入组 159 人开始时间: 2013年12月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
159
试验地点
1
主要终点
Area Under the Receiver Operating Curve (ROC) as a Measure of the Accuracy of the APACHE II and P-POSSUM Scoring Systems to Predict Mortality

研究概览

简要总结

To compare APACHE II and P-POSSUM scoring system in emergency laparotomy.

详细描述

To compare APACHE II and P-POSSUM scoring system in predicting postoperative mortality in patients undergoing emergency laparotomy.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • All patients above 18 years of age undergoing emergency laparotomy at Tata Main Hospital form 01st December 2013 to 30th November 2014 will be included in the study.

排除标准

  • Patients willingly seeking referral to a different hospital

结局指标

主要结局

Area Under the Receiver Operating Curve (ROC) as a Measure of the Accuracy of the APACHE II and P-POSSUM Scoring Systems to Predict Mortality

时间窗: 30 days

Participants will be followed for the duration of hospital stay (expected average of 30 days) and mortality was noted.All patients undergoing emergency laparotomy at Tata Main Hospital form 01st December 2013 to 30th November 2014 were included in the study. All patients were scored with APACHE II and P-POSSUM scoring systems on the day of surgery. Area under the curve (AUC) is used to measure the "size" of the prediction composed by the graphic display between the 'sensitivity' and the '1-specificity' relationship. AUC can range from 0.5 to 1.0 and a result of 1.0 indicates a perfect discriminatory ability. An AUC value \> 0.8 is considered good, a range between 0.60-0.80 is considered as moderate, and an AUC value \< 0.60 is regarded as poor. For APACHE-II, a cut off score of \>/=24 was determined; for P-POSSUM, a cut off score of \>/= 63 was determined.

次要结局

  • Length of Stay (LOS)(30 days)
  • Cardiac Morbidity (AMI or Arrhythmias Needing Treatment)(30 days)
  • Patients Needing Re-exploration(30 days)
  • Need for Postoperative Ventilator Support(30 days)
  • Need for Post Operative Inotropic Support(30 days)
  • Number of Participants With Acute Kidney Injury (AKI)(30 days)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dr.Deb Sanjay Nag

Associate Specialist

Tata Main Hospital

研究点 (1)

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