NCT03683537已完成不适用
Association Between Changes of GFAP After Surgery and Postoperative Delayed Cognitive Recovery
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Changes in serum GFAP
研究概览
简要总结
Assessment of serum level of glial fibrillary acidic protein (GFAP) before surgery (on the day of surgery), 24 hours after surgery and on 3 or 4 postoperative day. Neuropsychological testing before surgery and on 3 or 4 day after surgery. Investigation of relationship between changes of GFAP and scores of neuropsychological tests.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with different diseases, who require prolonged laparoscopy or open surgery
- •Age more than 60
- •ASA I-III
- •Informed consent to participate in the study
排除标准
- •Severe neurodegenerative or psychological diseases
结局指标
主要结局
Changes in serum GFAP
时间窗: 1 year
GFAP(3) - GFAP (1); GFAP (2) - GFAP (1)
次要结局
未报告次要终点
研究者
研究点 (1)
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