Effect of Prophylactic IV Ondansetron Prior Spinal Anaesthesia in Caesarean Section on Bradycardia and Hypotension (Observational Study)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 400
- 试验地点
- 1
- 主要终点
- Blood Pressure
研究概览
简要总结
Since Ondansetron is commonly used during cesarean deliveries to treat nausea and vomiting, this study will observe the correlation between ondansetron administration and effect on hemodynamics in order to confirm that the use of Ondansetron can reduce incidence of hypotension and bradycardia associated with spinal in cesarean section, and to identify the optimal timing and dose for administration.
详细描述
Hypothesis:
Administration of ondansetron prior to spinal anesthesia can attenuate hypotension and bradycardia.
Aim:
Since Ondansetron is commonly used during cesarean deliveries to treat nausea and vomiting, this study will observe the correlation between ondansetron administration and effect on hemodynamics in order to confirm that the use of Ondansetron can reduce incidence of hypotension and bradycardia associated with spinal in cesarean section, and to identify the optimal timing and dose for administration.
Objectives:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Pregnant patients undergoing elective caesarean section
排除标准
- •Preeclampsia
- •Eclampsia
- •Hypertension
结局指标
主要结局
Blood Pressure
时间窗: one hour
incidence of hypotension after spinal anaesthesia in the patients who received Ondansetron
次要结局
- Heart rate(One hour)
- Vasopressor(One hour)
研究者
Abdelrady S Ibrahim, MD
Professor of Anesthesia and ICU
Assiut University