ACTRN12619001228178已完成2 期
The physiochemical effects of a bicarbonate buffered solution versus Hartmann's solution during major abdominal surgery: a randomized, open-label, non-inferiorty study
Professor Rinaldo Bellomo0 个研究点目标入组 50 人开始时间: 2019年9月5日最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Adult aged 18 years or greater
- •Undergoing major abdominal surgery with an expected surgical duration of a minimum of 2 hours and an expected hospital admission of a minimum of 3 days
- •At risk of postoperative complications who have at least one of the following:
- •age equal to or greater than 70 years
- •known or document history of coronary artery disease
- •known or documented history of heart failure
- •diabetes with the receipt of oral hypoglycaemia agent and or insulin
- •preoperative serum creatinine greater than 200 micromol per litre
- •mobide obesity defined as a body mass index of equal to or greater than 35 kg per meter squared
- •peroperative serum albumin less than 30 gram/litre
- •anaerobic threshold of less than 12 ml per kilogram per minute
- •two or more of the following
- •ASA criteria 3 or 4
- •chronic respiratory disease
- •obesity of a body mass index between 30 and 35 kg per meter squared
- •aortic or peripheral vascular disease
- •preoperative haemoglobin less than 100 grams per litre
- •preoperative creatinine value of between 150-199 micromol/litre
- •anaerobic threshold 12-14 ml per kilogram per minute
排除标准
- •Urgent or time-critical surgery
- •ASA physical status 5
- •Chronic renal failure requiring dialysis
- •Pulmonary or cardiac surgery
- •Liver resection
- •Minor or intermediate surgery
研究者
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