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临床试验/CTRI/2018/06/014559
CTRI/2018/06/014559已完成2/3 期

A prospective double blind randomised control trial on efficacy of buffered 2% lignocaine with 1: 80,000 epinephrine versus non buffered solution

G Bharatiram1 个研究点 分布在 1 个国家目标入组 25 人开始时间: 2017年12月13日最近更新:

试验速览

阶段
2/3 期
状态
已完成
发起方
入组人数
25
试验地点
1
主要终点
Pain on injection with 5 point Likert Scale

研究概览

简要总结

The purpose of the study is to compare theanesthetic latency and injection pain for Buffered Local Anesthesia versus NonBuffered Local Anesthesia. In this double-blind, placebo-controlled, cross overinvestigation, 25 patients those requiring bilateral dental extractions underlocal anesthesia are selected. The sides of patients were randomized toBuffered Local Anesthesia or Non Buffered Local Anesthesia group. Evaluation ofpain on injection (carried out with the use of a  5- point Likert scale) and anestheticlatency  (time of onset) are carried out.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • Healthy participants those requiring bilateral dental extractions
  • Patients in the age group of 18- 50 years.

排除标准

  • Patients with debilitating systemic diseases
  • Patients with renal and cardiac problems
  • Pregnant women
  • Patients having abscess, cyst, space infections associated with teeth to be extracted.
  • Subjects who had analgesic or anti inflammatory drugs 24 hours before treatment 6.

结局指标

主要结局

Pain on injection with 5 point Likert Scale

时间窗: 3-120 seconds on injection

次要结局

  • Anesthetic latency (time of onset)

研究者

发起方
G Bharatiram
申办方类型
Other [self]

研究点 (1)

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