The Role of Blood Perfusion in Cervical Cancer, Cervical Intraepithelial Neoplasm and Ovarian Cancer Patients
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Vascularization-flow index
研究概览
简要总结
This study will elucidate the role of 3D transvaginal ultrasound in assessing (1) cervical vascularity and blood flow in patients with cervical cancer and cervical intraepithelial neoplasm, and (2) tumor vascularity and blood flow in patients with ovarian cancer.
详细描述
Patients and methods:
Women with cervical cancer, cervical intraepithelial neoplasm, ovarian cancer, or the control will be invited to particilate in this study.Then, 3D power Doppler Ultrasound will be performed to capture (1) the cervical volume, vascularity and blood perfusion, and (2) ovarian tumor vascularity and blood perfusion. The sonographic data will be correlated to clinical and pathological data.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Regarding the topic "Hemoperfusion characteristics of cervical cancer and precancerous lesions, and the correlation between hemoperfusion and prognosis":
- •Adult women who have had a normal cervical smear within the past three years and have no other gynecological cancers (control group).
- •Adult women with cervical cancer or precancerous lesions.
- •Regarding the topic "Correlation between hemoperfusion and prognosis of ovarian cancer":
- •Adult women suspected of having ovarian cancer, fallopian tube cancer, or peritoneal cancer before surgery.
排除标准
- •Regarding the topic "Hemoperfusion characteristics of cervical cancer and precancerous lesions of the cervix, and the correlation between hemoperfusion and prognosis":
- •1. Patients who cannot cooperate with vaginal 3D ultrasound scans.
- •Regarding the topic "Correlation between hemoperfusion and prognosis of ovarian cancer":
- •Patients who cannot cooperate with vaginal or abdominal 3D ultrasound scans.
研究组 & 干预措施
cervical cancer
cervical cancer patients
干预措施: Doppler ultrasound (Diagnostic Test)
cervical intraepithelial neoplasm
cervical intraepithelial neoplasm patients
干预措施: Doppler ultrasound (Diagnostic Test)
control
Gynecological patients without cervical disease
干预措施: Doppler ultrasound (Diagnostic Test)
ovarian cancer
ovarian cancer patients
干预措施: Doppler ultrasound (Diagnostic Test)
结局指标
主要结局
Vascularization-flow index
时间窗: 3 years
1. Compare the vascularization-flow index values between cervical cancer, cervical intraepithelial neoplasia and the control group. 2. To assess whether vascularization-flow index is a predictor of progression-free survival in women with ovarian cancer
次要结局
- Vascularization index(3 years)
- Flow index(3 years)
研究者
Sheng-Mou Hsiao, MD
Chief, Department of Obstetrics & Gynecology
Far Eastern Memorial Hospital