Effects of Gentian Violet Treatment on Patients With Hidradenitis Suppurativa
试验速览
- 阶段
- 2 期
- 状态
- 撤回
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Skin's Redness
研究概览
简要总结
This is a survey study being conducted to describe how subjects with Hidradenitis suppurativa (HS) respond to treatment with gentian violet. The study will rely primarily on qualitative survey responses and quantitative changes in skin appearance.
详细描述
Hidradenitis suppurativa (HS) is a chronic disease of the folliculopilosebaceous unit, often found in intertriginous areas of the body. The pain and impairment of HS leads patients to report a decreased quality of life, even in comparison to other debilitating cutaneous disease states. Pharmalogic management of HS can vary from topical antibiotics or intralesional corticosteroids for mild cases to immunosuppressants and biologic agents in refractory cases. Gentian violet is a topical antiseptic used to treat many cutaneous yeast infections. It also has a role in improving wound healing in sites of active ulceration. It is our hypothesis that gentian violet will help minimize skin trauma in sites of active HS to promote improved wound healing and quality of life.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 64 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients must have active HS, be willing to undergo one application of HS, and agree to follow-up in one month.
排除标准
- •Exclusion criteria include children, absent HS lesions at the time of clinic, and cognitive/physical impairments that would make them unable to assess quality of life factors of the survey.
研究组 & 干预措施
Gentian Violet Treatment
A single application of gentian violet will be topically applied to the site(s) of active HS involvement by a trained staff member. The sites will then be bandaged by staff and patients will be instructed about home maintenance procedures.
干预措施: Gentian Violet (Drug)
结局指标
主要结局
Skin's Redness
时间窗: 1 month post-treatment
Subjects rate skin redness at treatment site on a scale from 1 (no redness) to 5 (severe redness)
Skin's Drainage
时间窗: 1 month post-treatment
Subjects rate skin drainage at treatment site on a scale from 1 (no drainage) to 5 (severe drainage)
Skin's Pain
时间窗: 1 month post-treatment
Subjects rate skin pain at treatment site on a scale from 1 (no pain) to 5 (severe pain)
次要结局
未报告次要终点