Optimization Strategies for Pediatric Vaccination Scheduling in China: The Impact of Local Policies, Caregivers, Vaccination Staff, and the Cost-Effectiveness of Simultaneous and Combined Vaccinations
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 6,000
- 试验地点
- 1
- 主要终点
- The economic value of optimized vaccination scheduling strategies
研究概览
简要总结
This study aims to optimize pediatric vaccine scheduling in China . The first objective is to gather information on current vaccine schedules in China. The second objective is to evaluate the impact of simultaneous vaccination and combination vaccines on costs and vaccination rates through feedback from caregivers and vaccination staff.
详细描述
The first objective will comprehensively collect vaccination programs for children under 6 years old in all 31 provinces of China (excluding Hong Kong, Macau, and Taiwan), covering both NIP and non-NIP vaccines that are suitable for children. The second objective is to evaluate the impact of simultaneous vaccination and combination vaccines on costs and vaccination rates. This will involve analyzing vaccination coverage for simultaneous vaccines across different regions in China, as well as assessing caregivers' perspectives on simultaneous vaccination, including their willingness, preferences, and factors influencing their vaccination decisions. Additionally, the study will explore vaccination staff attitudes, recommendation behaviors, and their reasons for recommending simultaneous and combination vaccines. For the survey, the sample will consist of caregivers of children (aged between 2 to 59 months) from 10 representative provinces/municipalities/autonomous regions as well as vaccination staff from institutions in the respective regions.
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 2 Months 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •- For caregivers of children
- •Children aged ≥2 months and ≤59 months
- •Caregivers informed consent obtained For vaccination staff
- •All vaccination staff currently working at the selected community health service centers or township health clinics on the day of the survey For retrospective analysis
- •Children aged 5 years and under; with complete vaccination records. Complete vaccination records refer to a child having received all vaccines required by the NIP for their age group, with accurate dates recorded for each vaccination dose.
排除标准
- •- For caregivers of children
- •Caregivers who are unable to participate in the survey due to physical or other objective reasons
- •Caregivers with communication barriers
- •Caregivers who do not consent to participate in the survey For vaccination staff
- •Vaccination staff who do not consent to participate in the survey For retrospective analysis
- •Children whose vaccination records are missing or incomplete
- •Children whose vaccination has been delayed or not received due to medical contraindications.
结局指标
主要结局
The economic value of optimized vaccination scheduling strategies
时间窗: 2025.08-2025.09
This study will comprehensively collect vaccination programs for children under 6 years old in all 31 provinces of China (excluding Hong Kong, Macau, and Taiwan), covering both NIP and non-NIP vaccines that are suitable for children. The economic value of optimized vaccination scheduling strategies with simultaneous vaccination and combination vaccines will be assessed using a cost-minimization and budget impact model with inputs collected in this study. The optimized vaccination scheduling strategie will be collected in this study through a literature review, a cross-sectional caregiver survey, a survey among vaccination staff, and an observational time and motion chart among the latter population.
Caregivers' willingness to simultaneous vaccination and combined vaccines
时间窗: 2025.08-2025.09
To evaluate the acceptance and willingness of different vaccination strategies, the survey will collect caregivers' knowledge, attitudes, and preferences on optimized vaccine scheduling strategies including simultaneous vaccination and combination vaccines, as well as factors influencing their decisions , such as the vaccination status of siblings of other children and elderly family members over 60 years old. The primary outcome variable will be willingness to simultaneous vaccination and combined vaccines, assessed using a 5-point ordinal scale (from "very unwilling" to "very willing").
Immunization records and vaccination coverage
时间窗: 2025.08-2025.09
Using data collected from children's immunization records, a retrospective analysis will explore how previous simultaneous vaccination behaviors affect their vaccination rate. By comparing the vaccination rates at different ages between children receiving vaccines concomitantly vs. separately and children who uses combination vaccines vs. single vaccines, the study will evaluate whether the optimized vaccine scheduling strategies including simultaneous vaccination and combination vaccines have an impact on children's vaccination coverage.
次要结局
- Recommendation to simultaneous vaccination and combined vaccines(2025.08-2025.09)
- Vaccine hesitancy(2025.08-2025.09)