The Effects of Milk and Banana Given as a Night Meal to Individuals Diagnosed With Sleep Disorders on Sleep Quality, BDNF and Appetite Mechanism
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 21
- 试验地点
- 1
- 主要终点
- Level of Brain Derived Neurotrophic Factor (pg/ml)
研究概览
简要总结
The aim of this study to determine the impact of banana and milk on sleep and appetite
详细描述
Sleep is one of the main components of the continuity of circadian rhythm. It restores energy and enhancement, memory. Sleep disturbances and short sleep duration are important risk factors for many diseases. Nutrition is one of the main determinants of health status in many diseases related to inflammation. Especially the night meal, known as the foods consumed before bedtime, has a strong effect on sleep. Although there are methodological differences, most studies show that unhealthy eating habits are associated with short sleep duration. It is thought that consuming foods with high tryptophan and melatonin content can reduce sleep problems. This study will give a chance to observe the effects of nutrients on sleep and appetite mechanisms.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
盲法说明
ınvestigator
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Applying to the Sleep Polyclinic,
- •18-45 years old,
- •Body Mass Index (BMI) between 18.5-25 kg/m2,
- •Male and female patients diagnosed with primary sleep disorder for the first time
排除标准
- •Individuals with any psychiatric illness,
- •Those who use cigarettes, alcohol, drugs or sedative drugs,
- •Individuals with any chronic disease (diabetes, etc.),
- •Pregnant and/or lactating
- •Individuals with lactose intolerance,
- •athletes,
- •Individuals who are allergic to bananas
- •Individuals with lactose intolerance or milk intolerance
研究组 & 干预措施
eating banana for 6 weeks before bedtime
Participants will consume 1 portion of banana (gross 80-85 g) given to them for 6 weeks, approximately 45 minutes-1 hour before bedtime.
干预措施: Banana arm (Behavioral)
drinking milk for 6 weeks before bedtime
Participants will consume 200 ml of whole milk given to them for 6 weeks, approximately 45 minutes-1 hour before bedtime.
干预措施: Milk arm (Behavioral)
Control
Not making any changes in diet
干预措施: No intervention (Behavioral)
结局指标
主要结局
Level of Brain Derived Neurotrophic Factor (pg/ml)
时间窗: at baseline, 6. week
Fasting (less than 12 hrs) venous blood samples were collected from all the participants and centrifugation of the specimen was done (ng/ml)
Level of Leptin (mg/dl)
时间窗: at baseline, 6. week
Fasting (less than 12 hrs) venous blood samples were collected from all the participants and centrifugation of the specimen was done (ng/ml)
Evaluate stages of sleep and the oxygen level in blood
时间窗: at baseline and 6. week
Polymsomnography is used for the diagnosis and treatment plan of sleep disorder and sleep architecture
Changing Score on the Pittsburgh Sleep Quality Index (PSQI) from baseline
时间窗: at baseline, 6. week
Change from baseline PSQI at 6 weeks
Level of Ghrelin (mg/dl)
时间窗: at baseline and 6. week
Fasting (less than 12 hrs) venous blood samples were collected from all the participants and centrifugation of the specimen was done (ng/ml))
次要结局
- Nutrient intake (g/day)(6 consecutive weeks, 6 weeks)