跳至主要内容
临床试验/NCT01127711
NCT01127711已完成不适用

Cohort of Swedish Men

Karolinska Institutet0 个研究点目标入组 48,850 人开始时间: 1997年9月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
48,850
主要终点
Colorectal Cancer

研究概览

简要总结

The Cohort of Swedish Men began in 1997, when all men born between 1918 and 1952 and residing in two counties in central Sweden received a questionnaire including about 350 items concerning diet and other lifestyle factors. A second questionnaire was sent out in 2008-09.

详细描述

The Cohort of Swedish Men was established in 1997, when all men born between 1918 and 1952 and residing in Västmanland and Örebro counties in central Sweden received a questionnaire concerning diet and other lifestyle factors. Of the 100,303 eligible men, 48,850 (49%) responded to the questionnaire. The questionnaire included items about diet, physical activity, medical history, and lifestyle factors such as cigarette smoking history and use of dietary supplements.

During 2008-09, the exposure information was updated and extended by sending out two new questionnaires - one questionnaire on health including several signs of symptoms, sleeping, social relations etc (2008) and one on diet, dietary supplement use, and lifestyle factors (2009). Majority of questions in the questionnaires have been validated.

Incident cases of cancer are ascertained by record linkages of the study population with the National Swedish Cancer Register and the Regional Cancer Registers. Cardiovascular and other diseases as well as surgeries and causes of death are identified by linkage to the National Inpatient and other registries at the Swedish Board of Health and Welfare. Ascertainment of cancer cases and other diseases is almost 100% complete. Dates of deaths are ascertained through the Swedish Death Register (100% complete), and information on date of moving out of the study area is obtained by linkage with the Swedish Population Register.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
45 Years 至 79 Years(Adult, Older Adult)
性别
Male
接受健康志愿者

入选标准

  • All men born between 1918 and 1952, living in central Sweden

排除标准

  • 未提供

结局指标

主要结局

Colorectal Cancer

时间窗: 1997-2010

Prostate cancer

时间窗: 1997-2010

Pancreatic cancer

时间窗: 1997-2010

Stomach cancer

时间窗: 1997-2010

Bladder cancer

时间窗: 1997-2010

Fractures, hip fractures

时间窗: 1997-2014

Cataract

时间窗: 1997-2010

LUTS (Lower urinary tract symptom)

时间窗: 1997-2010

Cardiovascular Diseases

时间窗: 1997-2010

Mortality

时间窗: 1997-2010

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Alicja Wolk

Professor

Karolinska Institutet

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