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临床试验/NCT06709989
NCT06709989进行中(未招募)不适用

Expositions Chimique et Microbiologique Des Femmes Dans Les Exploitations Bovines laitières

Institut National de la Santé Et de la Recherche Médicale, France1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2025年1月3日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
发起方
入组人数
80
试验地点
1
主要终点
Exposure to chemicals of women working on dairy farms

研究概览

简要总结

Although professionals working on dairy cattle farms come into contact with a wide range of chemicals and microbiological agents, little is known about this possible exposure, which occurs a priori via inhalation and skin contact.

The aim of this research is to gain a better understanding of this chemical and microbiological exposure, and this research focuses in particular on professional women working on dairy cattle farms , who may be in charge of specific activities not commonly carried out by professional men.

Exposure to pesticides, antiparasitic products and disinfectants will be the first substances to be investigated, followed by other chemical or particulate compounds present in everyday and professional environments. Exposure to these compounds will be measured by their presence in the urine, feces (if possible) and hair of around 60 participating women, as well as in bovine tuft/head hair and, if possible, air samples taken in milking buildings.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Adult woman working on a dairy cattle farm in the "Grand Ouest" region of France
  • Woman who speaks and understands French

排除标准

  • working less than 20h/week in dairy farms
  • Woman under legal protection
  • unsigned consent form

结局指标

主要结局

Exposure to chemicals of women working on dairy farms

时间窗: At inclusion and at the end of the follow-up (for hair-concentrations), and during specific periods of agricultural activities (with two 4-day periods of urine sample collection, one period of faeces collection, and one week of environmental sampling)

Concentrations of pesticide molecules, biocides, disinfectants and microbiological agents, measured in * urines of professional women working on dairy farms, * the hair of professional women working on dairy farms, * faeces of professional women from dairy farms, * tuft/head hair from females in the herd on farms where female professionals work, * environmental samples of pesticide molecules (PPPs, pesticides), biocides, disinfectants and microbiological agents.

次要结局

  • Exposure to other chemicals(At inclusion and at the end of the follow-up (for hair-concentrations), and during specific periods of agricultural activities (with two 4-day periods of urine sample collection, one period of faeces collection, and one week of environmental sampling))

研究者

发起方
Institut National de la Santé Et de la Recherche Médicale, France
申办方类型
Other Gov
责任方
Sponsor

研究点 (1)

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