CTRI/2023/09/057923尚未招募3 期
Comparison of budesonide spray and water based as an endotracheal tube cuff lubricant on incidence of post operative sore throat:Randomized control study. - NI
DR SUMA CHAVADI0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Inclusion Criteria : 1) American socity of Anaesthesiolgist classification grade 1 and 2.
- •2)Eective surgery under general anaesthesia with endotracheal intubation not lasting for more than 3 hours.
- •A thorough pre anaesthetic evaluation will be done oery, nil per mouth status will be confirmed, and intravenous cannula will be secured. For all the patients, aspiration prophylaxis of IV Inj. Pantoprazole 40mg, and IV Inj. Ondansetron 8mg will be given. After shifting the patient to operation theatre, in all patients, pre medication of IV Inj. Glycopyrolate .005mg/kg, IV Inj. Midazolam .05mg/kg and IV Inj. Fentanyl 2mcg/kg. General anaesthesia will be induced with IV Inj. Propofol 2mg/kg with IV Inj. Succinylcholine 2mg/kg. Endotracheal cuff will be lubricated with Budesonide 200mcg spray in one group, and water based KY gel 82gm in another group. Intubation will be done. Anaesthesia will be maintained with titrated dose of Isoflurane, oxygen, and nitrous oxide. IV bolus of Inj. Vecuronium .1mg/kg or Inj. Atracurium .5mg/kg will be repeated intermittentanly to maintain muscle relaxation.
- •After adequate reversal at the end of surgery, thourough oropharyngeal suctioning, and regaining of consciousness, patient will be extubated, following which patient will be shifted to Post Anaesthtic Care Unit where post operative sore throat will be graded in the time intervals of immediately, 10 mins, 1st hour, 6th hour, and 24th hour after extubation.
排除标准
- •1)pre operative sore throat.
- •2)patients already pn a analgesic or steriods.
- •3)peptic ulcer and gastroesophageal reflux disease
- •4)Chronic lung disease.
- •5)Allergic to study drug
研究者
相似试验
已完成
3 期
Comparison of Budesonide and saline on weaning from Mechanical ventilatioweaning of mechanical ventilation.IRCT2016030920592N5Vice chancellor for research, Shahid Beheshti University of Medical Sciences120
尚未招募
不适用
Comparison of efficacy of budesonide dry powder inhaler and fuluticasone propionate dry powder inhaler in asthmatic children.-same dose studyasthmatic childrenJPRN-UMIN000005201Osaka Prefectural Medical Center for Respiratory and Allergic Diseases30
尚未招募
3 期
Budesonide MDI vs systemic steroids in COPDAE: a non-inferiority trialChronic obstructive pulmonary disease with mild to moderate acute exacerbationCOPDCOPDAEbudesonide MDIsystemic steroidsEDprednisolonedexamethasoneTCTR20201005006Routine to research unit, Faculty of medicine, Siriraj hospital120
已完成
不适用
To compare the reduction of pain during iv cannulation using Lidocine spray or Buzzy device with conventional means of IV cannulatioCTRI/2019/03/017967il105
招募中
不适用
Comparison of the effect of evaporative spray and music on paiIRCT20111019007844N13Bam University of Medical Sciences40