NCT02871544已完成不适用
Predictive Value of Dynamic Combination of B-type Natriuretic Peptide and Neutrophil Gelatinase-associated Lipocalin for the Prognosis of Patients With Sepsis
Southeast University, China0 个研究点目标入组 124 人开始时间: 2015年6月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 124
- 主要终点
- patient-ventilator synchrony for 30mins
研究概览
简要总结
Objective: to clarify the predictive value of brain natriuretic peptide (BNP) in combination with neutrophil gelatinase associated lipocalin (NGAL) for the prognosis of patients with sepsis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Factorial
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age ≥18 years and <85 years;
- •presence of severe sepsis according to Survival Sepsis Campaign 10;
- •all patients voluntarily joined this study with informed consents.
排除标准
- •participated in other trials within 30 days before the criteria for this trial were met;
- •expected to die within 24 hours;
- •pregnant;
- •advanced malignancy with life expectancy <6 months;
- •history of congestive heart failure;
- •chronic renal dysfunction (baseline creatinine >176.8μmol/L); and
- •relatives were unwilling to agree to the use of full life support.
结局指标
主要结局
patient-ventilator synchrony for 30mins
时间窗: 30mins after the patients involved
次要结局
- 28-day mortality(28 days after the patients involved)
- Mechanical ventilation duration between day 1 and day 28(days of mechanical ventilation between day 1 and day 28)
- the numbers of days in the ICU between day 1 and day 28(the numbers of days in the ICU until day 28)
研究者
Chun Pan
Dr
Zhongda Hospital
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