NCT00899327Unknown不适用
Molecular and Functional Characterisation of Bone Marrow Function in Normal Subjects, Myelodysplastic Syndromes (MDS) and Secondary Disorders of Heamatopoiesis
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Identification of novel biomarkers of disease
研究概览
简要总结
RATIONALE: Studying samples of blood and bone marrow in the laboratory from patients at risk of developing myelodysplastic syndrome may help doctors learn more about changes that occur in DNA and identify biomarkers related to disorders of the blood and bone marrow.
PURPOSE: This research study is looking at biomarkers in patients at risk of developing myelodysplastic syndrome or other disorders and in healthy participants.
详细描述
OBJECTIVES:
Primary
- To identify novel biomarkers of disease that would help in the initial diagnosis of myelodysplastic syndromes (MDS).
Secondary
- To understand the genesis of anemia in cancers.
- To identify novel biomarkers of disease that predict progression of MDS to acute myeloid leukemia.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Identification of novel biomarkers of disease
次要结局
- Identification of novel biomarkers of disease progression from myelodysplastic syndromes to acute myeloid leukemia
- Comprehension of genesis of anemia in cancer
研究者
研究点 (1)
Loading locations...
相似试验
招募中
不适用
Skeletal Health and Bone Marrow Composition in Newly Diagnosed Adolescents With Crohn DiseaseCrohn DiseaseInflammatory Bowel DiseaseNCT04508088Massachusetts General Hospital92
招募中
不适用
Skeletal Health and Bone Marrow Composition in Adolescents With Cystic FibrosisCystic FibrosisNCT06216704Massachusetts General Hospital36
招募中
不适用
Characterizing the bone marrow environment in advanced-stage myelofibrosis. A PET/MRI study.Myelofibrosis. Myelofibrose.Ruxolitinib.PETMRINL-OMON20797VU University Medical Center6
已完成
不适用
S9031-9333-0106-0112-A Study of Biomarkers in Samples From Patients With Acute Myeloid Leukemia Treated With Standard Chemotherapy With or Without Gemtuzumab OzogamicinLeukemiaNCT01503541SWOG Cancer Research Network365
已完成
不适用
DNA Analysis of Bone Marrow and Blood Samples From Young Patients With Acute Myeloid Leukemia or Acute Lymphoblastic LeukemiaLeukemiaNCT00899652Children's Oncology Group149