Fractal Analysis of Mandibular Trabecular Bone Changes in Complete Denture Patients Restored With Pre-polymerized Milled PMMA Compared With Light-cured 3D-printed Teeth: a Split-mouth Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Bone Density
研究概览
简要总结
Although the number of individuals who are edentulous is declining, a sizable fraction still needs a complete denture for their oral rehabilitation.Tooth loss is an issue in public health that determines quality of life since it is linked to socioeconomic, physiological, and psychological aspects. In patients who are completely edentulous, dental implants have been viewed as a favorable choice for rehabilitation.
详细描述
Although the number of individuals who are edentulous is declining, a sizable fraction still needs a complete denture for their oral rehabilitation.Tooth loss is an issue in public health that determines quality of life since it is linked to socioeconomic, physiological, and psychological aspects. In patients who are completely edentulous, dental implants have been viewed as a favorable choice for rehabilitation.
There have been various occlusion schemes proposed. The term "lingual occlusion," or "LO," was first used in 1941 to describe the occlusion of the mandibular occlusal surfaces with the maxillary lingual cusps in a central and non-centric relationship. This makes it simpler to acquire both the dental position and the occlusal scheme LO.
DeVan suggested the neutral-centric or zero-degree (ZD) occlusion method, in which the cusps are at a zero-degree inclination to balance the incline, centralise the masticatory power, and get around the challenge of attaining precise jaw relations. Moreover, compared to cusped teeth, teeth with a zero-degree occlusal angle exert less pressure on the soft tissues. 13,14 The optimal occlusal scheme in terms of masticatory performance and patient quality of life/satisfaction, however, has not been determined.
Many radiomorphometric studies have employed digital panoramic radiographs to predict osteoporosis based on BMD levels. Dental professionals may employ the mandibular cortical width (MCW), panoramic mandibular index, and Klemetti index as general useful methods to screen for low BMD and anticipate osteoporosis. The meta-analysis determined that the erosion of mandibular cortical bone had an estimated sensitivity and specificity in identifying osteoporosis of 0.806 and 0.643, respectively.
Because individuals with cortical width more than 4 mm typically have normal BMD, MCW also exhibits improved specificity in eliminating osteopenia/osteoporosis. It will be extremely helpful for the initial screening of the osteoporosis risk and advising the assessment of further clinical risk factors to prevent osteoporotic fracture because the panoramic radiograph is frequently employed as a diagnostic tool in dental practice.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 45 Years 至 75 Years(Adult, Older Adult)
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Completely edentulous patients ranging from age 45 to 75 years
- •Angle's Class I skeletal relationship
- •Normal facial symmetry
- •Cooperative patients
- •Adequate inter-arch space not less than 12mm
排除标准
- •Temporomandibular disorders
- •Uncontrolled diabetes
- •Bleeding disorders or anticoagulant therapy
- •Flabby tissues or sharp mandibular residual ridge.
- •Heavy smokers.
- •Patient's with neuromuscular disorders
- •Patients on chemotherapy or radiotherapy
- •Severe psychiatric disorders
- •Angle's class II and III skeletal relationship
研究组 & 干预措施
Control
This study included complete denture wearers undergoing mandibular rehabilitation in a split-mouth randomized clinical trial. The two prosthetic conditions were applied intra-individually on opposite sides, allowing direct comparison of the effect of prepolymerized milled PMMA denture teeth on mandibular trabecular bone architecture as assessed by fractal analysis.
干预措施: Prepolymerized milled PMMA with light-cured 3D-printed denture teeth. (Device)
Test
This study included complete denture wearers undergoing mandibular rehabilitation in a split-mouth randomized clinical trial. The two prosthetic conditions were applied intra-individually on opposite sides, allowing direct comparison of the effect of light-cured 3D-printed denture teeth on mandibular trabecular bone architecture as assessed by fractal analysis.
干预措施: Prepolymerized milled PMMA with light-cured 3D-printed denture teeth. (Device)
结局指标
主要结局
Bone Density
时间窗: 6 months
Fractal analysis of OPG of mandibular bone
Trabecular bone changes
时间窗: 48 months
Fractal analysis of CBCT in mandibular bone
次要结局
未报告次要终点
研究者
Shady El Naggar
Associate Professor
Badr University
