Arm Swing During Walking in Early Multiple Sclerosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Arm swing amplitude-shoulder degrees in flexion-extension direction
研究概览
简要总结
Multiple sclerosis (MS) is the most common central nervous system inflammatory demyelinating disease which causes motor and sensory deficits, cerebellar symptoms, and balance problems. Due to these symptoms, gait abnormalities are common in MS, even in patients with low degrees of impairment. The upper limb has an important role on postural control and gait stability. Affected arm swing movement and asymmetry during gait are common in neurological disorders such as Parkinson's disease (PD) even in early stages of the disease and arm swing treatment has been acknowledged to enhance gait and normalize arm swing in individuals with PD.
The presence of arm swing changes during walking in MS patients, similar to PD, especially in the early period, may be an indicator of balance problems, this was, however, not investigated as such. Therefore, the aim of the current study is to assess the arm swing during gait in people with MS shortly after their diagnosis in early MS.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients who were diagnosed with MS in the last 30 days,
- •Patients who were recovered from their symptoms and were clinically stable
排除标准
- •Patients who had an acute medical illness in the past 6 months, any other neurological and psychiatric diseases
- •Patients who had any orthopedic, rheumatologic, or vestibular conditions that affect walking
- •Patients who had exacerbations between the first and second evaluations
结局指标
主要结局
Arm swing amplitude-shoulder degrees in flexion-extension direction
时间窗: 3 months after the baseline
The difference between the maximum flexion and extension of the shoulder will be calculated with Kinovea video player.
Arm swing amplitude-elbow degrees in flexion-extension direction
时间窗: 3 months after the baseline
The difference between the maximum flexion and extension of the shoulder will be calculated with Kinovea video player.
Arm swing amplitude-overall degrees in flexion-extension direction
时间窗: 3 months after the baseline
The difference between the maximum flexion and extension of the shoulder will be calculated with Kinovea video player.
Step-speed
时间窗: 3 months after the baseline
The stepping task required patients to walk back and forth for 2 minutes over a three meters walkway which was set up with the FreeMed foot pressure analysis system (Sensor Medica, Guidonia Montecelio). Step speed outcome was collected from foot pressure analysis system.
Two Minute Walk Test (2MWT)
时间窗: 3 months after the baseline
It is a measure of self-paced walking ability and functional capacity. The person is encouraged to walk as fast as they can, safely, without assistance for two minutes and the distance is measured.
Timed Up and Go (TUG)
时间窗: 3 months after the baseline
To determine fall risk and measure the progress of balance, sit to stand and walking.It uses the time that a person takes to rise from a chair, walk three meters, turn around 180 degrees, walk back to the chair, and sit down while turning 180 degrees.
Timed 25Foot Walk Test (T25FW)
时间窗: 3 months after the baseline
The T25-FW is a quantitative mobility and leg function performance test based on a timed 25-walk.
次要结局
未报告次要终点
研究者
Gokce Leblebici
Physiotherapist
Istanbul Medeniyet University