DRKS00003537已完成未知
In-vivo-quantification of both serotonin-and norepinephrin-transporter availability in obese persons without co-morbid depression using positron emission tomography (PET) and selective radio-labelled markers - comparison with healthy controls and 6 months after a multimodal treatment program - IFB-PET
niversitätsklinikum Leipzig AöRKlinik und Poliklinik für Nuklearmedizin0 个研究点目标入组 65 人开始时间: 2012年5月30日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 65
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomized controlled study
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 65 Years（—）
- 性别
- All
入选标准
- •Age between 18 and 65
- •BMI > 35 kg/m2 resp. <30 kg/m2
- •no psychotropic-medication and/or drugs for at least 8 weeks prior PET
- •written informed consent
排除标准
- •History of neurological or psychiatric diseases
- •juvenile-onset diabetes (type 1) resp. insulin dependent diabetes type 2, malignant hypertension
- •medical treatment or surgery for weight reduction less then 6 months ago
- •Structural lesions (stroke, traumatic brain injury etc.)
- •Cognitive deficits, major speech impairment, alcohol- or drug abuse (positive drug test)
- •Major mental disorders, major communicative deficiencies which inhibit an informed consent
- •neurosurgical interventions in the past
- •Epilepsy, cerebral seizures in previous medical history (or in history of the family)
- •Chronic diseases (e.g. asthma) indicating chronic medical treatment with central effect
- •Pregnancy (exclusion via urine test before the experiment)
- •Contraindications for MR imaging (e.g., implanted ferro-magnetic devices), claustrophobia
研究者
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