EUCTR2009-017842-30-GB进行中（未招募）1 期
A randomised, double-blind, placebo-controlled trial to compare the early administration of intravenous haloperidol versus placebo in the prevention and treatment of delirium in critically ill ventilated patients - HalOPeridol Effectiveness in ICU delirium - the HOPE-ICU trial
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 142
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
入选标准
- •Mechanically ventilated patients in the Intensive Care Unit within 72 hours of admission.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Allergy to haloperidol, chronic antipsychotic use, corrected QTc interval (QTc) over 500 msecs, history of torsades de pointes or neuroleptic malignant syndrome, age less than 18 years, pregnancy, structural brain damage, patients with dementia, patients with Parkinsons Disease, moribund patients not expected to survive 48 hours, patients who do not understand English, patients predicted to stay less than 48 hours, and elective uncomplicated surgery.
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