Sensitization to Animal Allergens and Allergic Symptoms During Exposure to Animal Allergens in Korean Veterinary Researcher
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 135
- 试验地点
- 1
- 主要终点
- Skin reactivity to animal allergen in skin prick test
研究概览
简要总结
The investigators will evaluate sensitization to animal allergens and allergic symptom during contacting animal allergens in Korean veterinary researchers who attend their annual conference.
The investigators will compare sensitization to animal allergen and other clinical and occupational factors between subjects who suffer from allergic symptom during contacting animal and those who do not.
详细描述
The investigators will visit annual conference of Korean veterinary researchers.
After informed consent, Korean veterinary researchers who attend their conference and agree to enrollment into this study will be asked to respond to questionnaires regarding their gender, age, underlying allergic diseases, family history of allergic diseases, occupation and it's duration, contact animal and contact duration. Subjects will also be requested to report allergic symptom, causal animal and situation of contact including veterinary service, animal experiment, pet ownership, and ingestion if subjects suffer from allergic symptom when subjects contact animal.
Then, subjects will also be asked to undergo skin prick test for animal allergens including chicken feather and ten mammal epithelia as well as cow's milk, and hen's egg, four fish flesh and seven animal meats.
subjects will be divided into two group, subjects who suffer from allergic symptom during contacting animal and those who do not. Between two groups, sensitization to animal allergens as well as other demographic and occupational factors including gender, age, underlying allergic diseases, family history of allergic diseases, occupation and it's duration, contact animal and contact duration will be compared.
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Veterinary researchers attending their annual conference
排除标准
- •Veterinary researchers who receive medication including antihistamine (H1 and H2 blocker), systemic glucocorticosteroid which can effect on the result of skin prick test
- •Veterinary researchers who do not want to participate in this study
结局指标
主要结局
Skin reactivity to animal allergen in skin prick test
时间窗: on the day of survey (day 1)
Mean diameter of wheal for animal allergen in skin prick test
次要结局
- Contact animal(on the day of survey (day 1))
- Underlying allergic disease(on the day of survey (day 1))
- Family history of allergic disease(on the day of survey (day 1))
- Occupation(on the day of survey (day 1))
- Causal animal(on the day of survey (day 1))
- Allergic symptom during contacting animal(on the day of survey (day 1))
- Duration of occupation(on the day of survey (day 1))
- Contact time(on the day of survey (day 1))
- Contact situation(on the day of survey (day 1))
研究者
Sang Min Lee
Assistant professor
Gachon University Gil Medical Center