NCT06151379已完成不适用
The Relation Between the Initial Value of the Skeletal Mass Index and Pathological Response
Acıbadem Atunizade Hospital1 个研究点 分布在 1 个国家目标入组 69 人开始时间: 2023年3月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 69
- 试验地点
- 1
- 主要终点
- Sarcopenic index
研究概览
简要总结
The investigators aimed to accurately measure muscle mass and predict pCR to NAC and its effect on clinical outcomes.
详细描述
In patients with operable breast cancer (BC) receiving neoadjuvant chemotherapy (NAC), the pathological response rate was found to be related to body composition. The success of complete pathologic response (pCR) is a known prognostic factor in BC patients treated with NAC. The investigators aimed to accurately measure muscle mass and predict pCR to NAC and its effect on clinical outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 29 Years 至 72 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Early and locally advanced operated breast cancer patients receiving neoadjuvant chemotherapy.
排除标准
- •Patients who did not receive neoadjuvant chemotherapy, had metastatic breast cancer and whose radiological images were not available.
结局指标
主要结局
Sarcopenic index
时间窗: Through study completion, an average of 1 year.
skeletal muscle area (cm2)/height (m2) et L3 level
次要结局
- Body mass index(Through study completion, an average of 1 year.)
研究者
Ebru Yilmaz
Principal Investigator
Acıbadem Atunizade Hospital
研究点 (1)
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